Measles inclusion body encephalitis (MIBE) is a disease of the immunocompromised host and typically occurs within 1 year of acute measles infection or vaccination. We report a 13-year-old boy who had chronic granulomatous disease and presented 38 days after stem cell transplantation with afebrile focal seizures that progressed despite multiple anticonvulsants. After an extensive diagnostic eval...

Candida albicans is both the most common fungal commensal microorganism in healthy individuals and the major fungal pathogen causing high mortality in at-risk populations, especially immunocompromised patients. In this review, we summarize the interplay between the host innate system and C. albicans, ranging from how the host recognizes, responds, and clears C. albicans infection to how C. albi...

Preparing the books to read every day is enjoyable for many people. However, there are still many people who also don't like reading. This is a problem. But, when you can support others to start reading, it will be better. One of the books that can be recommended for new readers is approach to pulmonary infections in the immunocompromised host. This book is not kind of difficult book to read. I...

A 26 year old pregnant woman with antithrombin III deficiency developed recurrent septicaemia with Serratia marcescens. In spite of the administration of antibiotics, high grade fever persisted. She subsequently manifested lower abdominal pain, and spontaneous abortion occurred. After the abortion, she became completely afebrile. The amnion was turbid, and microscopic examination of the placent...

Otomycosis is a fungal infection of the external ear; middle ear and open mastoid cavity.1 Meyer first described the fungal infection of the external ear canal in 1884. External ear canal has an ideal warm humid environment for the proliferation of fungus.2 Although this disease is rarely life threatening, it can presents a challenging and frustrating situation for the otologist and patients du...

To cite: Shahani L. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014208822 DESCRIPTION A 71-year-old man with newly diagnosed, untreated acute myeloid leukaemia presented with fever, cough and confusion. Complete blood count showed neutropenia (90 cells/mm), lymphopenia (350 cells/mm) and 90% circulating blast. Initial chest X-ray showed evidence of new right ...

Fungal infections of the immunocompromised host are being seen with greater frequency than ever before. In addition, a growing list of unusual and unexpected etiologic agents presents a unique and difficult challenge to the clinician and microbiologist. The clinical manifestations of opportunistic fungal infections are often not characteristic and, in many instances, may prevent a rapid diagnos...

the treatment of obesity hypoventilation syndrome without severe nocturnal desaturation. Thorax 2008;63:395–401. 80. Storre JH, Seuthe B, Fiechter R, et al. Average volume-assured pressure support in obesity hypoventilation: a randomized crossover trial. Chest 2006;130:815–21. 81. Mokhlesi B. Positive airway pressure titration in obesity hypoventilation syndrome: continuous positive airway pres...

Dexamethasone was given to mice infected with Toxoplasma gondii to provide a model of recrudescence of infection in immunocompromised patients and to permit investigation of the interaction between parasite and host.