Astrocytoma as one of the most common central nervous system (CNS) tumors is rarely reported in veterinary literature. A 7-year-old Persian Lori-Bakhtiari ewe was presented to the clinic with a two months history of progressive blindness, nystagmus to the right, bilaterally decreased pupillary reflexes, head pressing and paddling. At necropsy, a whitish well-circumscribed mass with dimensions o...

myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. in this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoid myoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass with progressive growth for one month who was admitted in alzahra hospital of isfahan university of medical sc...

Background: Giant cell tumor of bone is a locally aggressive, rarely metastasizing that accounts for about 5% tumors and generally occurs in patients between 20 45 years old. A driver mutation the histone 3.3 (H3.3) gene H3F3A has been identified as many 96% giant bone. The immunohistochemical expression H3.3 G34 was found 97.8% cases. In present study, we describe our series cases pediatric &l...

AFX: atypical fibroxanthoma HMWK: high molecular weight keratins IHC: immunohistochemical MMS: Mohs surgery SCC: squamous cell carcinoma INTRODUCTION Poorly differentiated spindle cell neoplasms pose a diagnostic challenge for dermatopathologists because of a lack of specific morphologic features on standard histopathology. Further characterization with immunohistochemical (IHC) studies is freq...

ABSTRACT: Bovine cutaneous angiomatosis (BCA) is a rare condition characterized by vasoproliferative skin lesions mainly affecting cattle in the northern hemisphere. An eight-month-old Holstein heifer showed two easy-bleeding nodules bulging from epidermis forehead and close to right prescapular region. Skin were within dermis had an irregular surface soft heterogeneous reddish parenchyma compo...

Diffuse large B-cell lymphoma (DLBCL) of the heart accounts for only 1% primary cardiac tumors. Histopathologic examination becomes key diagnosis and immunohistochemical evaluation non-Hodgkin (NHL) subtype determination is able to predict disease progression therapeutical modality. Case description: 70-year-old man complained shortness breath. Echocardiographic revealed mass occupied left atri...

Background: Colorectal carcinoma (CRC) is one of the most common human cancers. It fourth cause death from cancer. cancer third in men and second women worldwide. Objective: To evaluate immunohistochemical expression KAI-1/CD82 different stages colorectal to biological behavior tumor target therapy. Patients Methods: Thirty formalin-fixed, paraffin-embedded tissue (obtained archive Al-Azhar Uni...

Recently, IL4Rα, IL13Rα1, and constituents of type II IL4 receptors are involved in the progression human cancers through activation JAK2 pathway. However, studies on IL4Rα IL13Rα1 gallbladder (GB) have been limited. To investigate expression 122 GB carcinomas effect inhibition SNU308 cancer cells. In carcinomas, were evaluated with immunohistochemical staining tissue microarray sections. Immun...

the effect of a neuropeptide, the tachykinin on α-amylase, protease and lipase activities in the midgut of american cockroach, periplaneta americana (linnaeus) is evaluated . immunohistochemical reactivities against tachykinin (tachykinin- ir) were detected in the midgut. tachykinin-ir cells in three regions (anterior, median and posterior) of the midgut were counted in normally fed, starved fo...

the study was undertaken to answer the question that how many patients with pigmentation of back and arms actually have amyloid deposits in pathology. 44 patients presenting with diffuse pigmentation of back and arms (dpoba) were selected. skin biopsies were performed in all cases from the affected sites. on all formalin fixed and paraffin embedded specimens, the following histochemical stains ...