نتایج جستجو برای: immunohistochemical ihc profile

تعداد نتایج: 267307  

2017
Kiwon Han Hwi Won Seo Yeonsu Oh Ikjae Kang Changhoon Park Sang Hoon Kang Sung-Hoon Kim Bog-Hieu Lee Byung Joon Kwon Chanhee Chae

The objective of the present study was to compare the ability of 2 monoclonal antibodies (mAbs; SDOW17 and SR30) to detect types 1 and 2 Porcine reproductive and respiratory syndrome virus (PRRSV) in formalin-fixed, paraffin-embedded (FFPE) lung tissues by immunohistochemistry (IHC) and to compare the immunohistochemical results with in situ hybridization (ISH) and reverse transcription nested ...

2017
Jiyoon Jung Youngjin Kang Yoo Jin Lee Eojin Kim Bokyung Ahn Eunjung Lee Joo Young Kim Jeong Hyeon Lee Youngseok Lee Chul Hwan Kim Yang-Seok Chae

BACKGROUND Colorectal cancer (CRC) is one of the most common malignancies worldwide. Approximately 10%-15% of the CRC cases have defective DNA mismatch repair (MMR) genes. Although the high level of microsatellite instability status is a predictor of favorable outcome in primary CRC, little is known about its frequency and importance in secondary CRC. Immunohistochemical staining (IHC) for MMR ...

Journal: :Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2012
Kiwon Han Hwi Won Seo Yeonsu Oh Ikjae Kang Changhoon Park Sang Hoon Kang Sung-Hoon Kim Bog-Hieu Lee Byungjoon Kwon Chanhee Chae

The objective of the present study was to compare the ability of 2 monoclonal antibodies (mAbs; SDOW17 and SR30) to detect types 1 and 2 Porcine reproductive and respiratory syndrome virus (PRRSV) in formalin-fixed, paraffin-embedded (FFPE) lung tissues by immunohistochemistry (IHC) and to compare the immunohistochemical results with in situ hybridization (ISH) and reverse transcription nested ...

2016
Sara Notaro Daniel Reimer Michaela Duggan-Peer Heidi Fiegl Annamarie Wiedermair Julia Rössler Peter Altevogt Christian Marth Alain Gustave Zeimet

BACKGROUND Management of endometrial carcinoma (EC) still needs improvement of risk assessment. Recently, L1CAM immunohistochemical (IHC) evaluation showed a unique value to predict the outcome of early EC. However IHC results are often conflicting for lack of inter-laboratory standardisation. METHODS Here, as a proof of concept and to increase reproducibility we assayed eighty-two EC and 26 ...

2015
Sydney Dubois Sylvain Mareschal Jean-Michel Picquenot Pierre-Julien Viailly Elodie Bohers Marie Cornic Philippe Bertrand Elena Liana Veresezan Philippe Ruminy Catherine Maingonnat Vinciane Marchand Hélène Lanic Dominique Penther Christian Bastard Hervé Tilly Fabrice Jardin

Enhancer of Zeste Homolog 2 (EZH2) plays an essential epigenetic role in Diffuse Large B Cell Lymphoma (DLBCL) development. Recurrent somatic heterozygous gain-of-function mutations of EZH2 have been identified in DLBCL, most notably affecting tyrosine 641 (Y641), inducing hyper-trimethylation of H3K27 (H3K27me3). Novel EZH2 inhibitors are being tested in phase 1 and 2 clinical trials but no st...

2016
Nasser Rakhshani Mohammadreza Araste Farid Imanzade Mahshid Panahi Fahimeh Safarnezhad Tameshkel Masoud Reza Sohrabi Mohammad Hadi Karbalaie Niya Farhad Zamani

BACKGROUND Hirschsprung disease is a complex genetic disorder of the enteric nervous system (ENS), often called congenital aganglionic megacolon and characterized by the absence of enteric neurons along a variable length of the intestine. The definitive diagnosis of Hirschsprung disease relies on histologic and/or histochemical staining of sections from suction rectal biopsies. Calretinin immun...

Journal: :The Journal of general virology 2002
Margaret A Wild Terry R Spraker Christina J Sigurdson Katherine I O'Rourke Michael W Miller

The usefulness of tonsillar biopsy on live deer for preclinical diagnosis of the transmissible spongiform encephalopathy chronic wasting disease (CWD) was evaluated. Disease was tracked in a CWD-endemic herd using serial tonsillar biopsies collected at 6 to 9 month intervals from 34 captive mule deer (Odocoileus hemionus) and five white-tailed deer (O. virginianus). Tonsillar biopsies were exam...

2017
Joseph de Nanassy Dina El Demellawy

Immunohistochemical (IHC) stains are widely used by pathologists for a variety of considerations in the diagnostic workup of pediatric nonneoplastic lesions in gastrointestinal (GI), hepatic, biliary, and pancreatic lesions. The pathologic changes cover a wide range and types of presentations, including inflammatory (bacterial and viral), metaplastic, posttransplant lymphoproliferative, autoimm...

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