We evaluate the ability of hexahistidine (His6) tags on peptide and protein substrates to recruit deoxyribozymes for modifying those substrates. For two different deoxyribozymes, one that creates tyrosine-RNA nucleopeptides and another that phosphorylates tyrosine side chains, we find substantial improvements in yield, kobs, and Km for peptide substrates due to recruiting by His6/Cu(2+). Howeve...

one of the most important issues in philosophy of religion is theanthropology, because the human being is both receiver and addresseeof religion. our view to religion can be changed by our view to human.the present article wants to compare the insight of twophilosophers-one of them from the east and the other from the west. mulla-sadra with the presentation of motion in substance in the center ...

according to the philosophical principles of higher wisdom (motealiyeh), especially the theory of substantial movement (hareka fil-jawhar) and psychology, it look impossible for human being to return to worldly life after his/her death. so refutation of the theory of reincarnation in the sadra’s system will not be very hard, especially when considering the rule of impossibility of return (emten...

This paper explains the continuing relevance of Keynes’s philosophical thinking in terms of his anticipation of complexity thinking in economics. It argues that that reflexivity is a central feature of the philosophical foundations of complexity theory, and shows that Keynes employed an understanding of reflexivity in both his philosophical and economic thinking. This argument is first develope...

From the arrangement of individual phrases to the grand structure of the entire poem, Lucretius uses poetic form with economy and imagination to attract the reader’s attention and to drive home his philosophical message. In their main lines, the structure and content of the poem’s argument derive from earlier Epicurean and other philosophical models, and Lucretius’ debts to some of his predeces...

We present a molecular theory to study the adsorption of different species within pH-sensitive hydrogel nanofilms. The theoretical framework allows for a molecular-level description of all the components of the system, and it explicitly accounts for the acid-base equilibrium. We concentrate on the adsorption of hexahistidine, one of the most widely used tags in bio-related systems, particularly...

attention to Cullen's metaphysics, shared to a great extent with David Hume and Adam Smith, reveals a larger project, the endorsement of learning, enquiry, and progress. Cullen, it might be said, was creating the role of the philosophical doctor as well as that of the philosophical chemist. Gunter Risse is interesting on Cullen as a clinician. Risse shows there were significant differences betw...

iqballahoori is one of those muslim and undertaking thinkers and poets who has not restricted himself to one language and territory, but his thoughts and ideas have moved over all ethnical and religious boundaries. adhered tightly to his poetic message and inspired by clean revelation sources and having unbreakable bond with pure religious thoughts, he has left an everlasting literary work whos...