BACKGROUND AND AIMS Doxorubicin is a potent anticancer drug and a major limiting factor that hinders therapeutic use as its high levels of systemic circulation often associated with various off-target effects, particularly cardiotoxicity. The present study focuses on evaluation of the efficacy of doxorubicin when it is loaded into the protein nanoparticles and delivered intravenously in rats be...

Caloric restriction has been associated with a delay in the development of both spontaneous and induced neoplasia. In contrast, cycles of fasting/refeeding were shown by us and others to enhance the incidence of early lesions during chemical carcinogenesis in rat liver. The present, long-term study was undertaken to establish whether such a diffential effect would also extend to the later phase...

the present study aimed at investigating the effect of different levels of nitrogen on yield and yield components of bread and durum wheat. to this end the experiment was conducted in 2010-2011 in south west of iran as split plots based on randomized complete block design with three replications. main plot included four levels of nitrogen 60, 120, 180, 240 kg.ha-1 and the sub plot included four...

Abstract South Sulawesi has long been known as the largest soybean-producing province in Indonesia and one of its supporters is emergence several soybean varieties that have responsiveness adaptability to various agroecosystems are tolerant pests diseases. Several developed by farmers brought be producer include Wilis, Mahameru, Anjasmoro, Argomulyo. The Wilis variety emerged a superior era 198...

The title compound, [Cu(C7H4ClO2)2(C10H14N2O)2(H2O)], has twofold symmetry with the Cu(II) cation and the O atom of the coordinating water mol-ecule located on the axis. The Cu(II) cation is coordinated by two carboxyl-ate O atoms of chloro-benzoate (CB) anions, two N atoms of N,N-di-ethyl-nicotinamide (DENA) ligands and one water mol-ecule in a distorted N2O3 square-pyramidal geometry. The ben...

A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different initiators. One study with 2 mT applied on DMBA-initiated mice may suggest a copro...