The historical items pertaining to mercury are outlined, and its toxicity and former medicinal uses are discussed. The diversity of the toxic effects by the different forms of mercury as well as the routes of administration are illustrated in three case reports. The importance of diaphoresis in the treatment of mercury poisoning as well as the status of the use of chelating agents are reviewed....

Veratrone is prepared from veratrum viride. It is described as being an aseptic, non-alcoholic, physiologically standardised preparation. Each cubic centimetre represents 0-25 gram, of the drug. It is standardised to a definite degree of activity by physiological tests. It contains a small proportion of chloretone, which acts as a preservative. The patient should always be kept in the recumbent...

BACKGROUND An otherwise successfully performed endoscopic thoracic sympathectomy (ETS) to treat palmar hyperhidrosis (PH) often has a serious side effect: compensatory sweating (CS). This side effect occurs in other parts of the body to a disturbing extent. The objective of this study is to determine whether there is a relationship between the level of ETS performed on patients with PH, and the...

Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal adverse event associated with the use of antipsychotics. Although atypical antipsychotics were initially considered to carry no risk of NMS, reports have accumulated over time implicating them in NMS causation. Almost all atypical antipsychotics have been reported to be associated with NMS. The clinical profile of NMS caused b...

BACKGROUND Primary palmar and/or axillary focal hyperhidrosis is a frequent disorder characterized by excessive sweating beyond physiological needs, often leading to a substantial impairment of quality of life. Over the years several minimally invasive surgical treatments have been described, however results vary, and due to a lack of uniform surgical approach, technique and nomenclature are of...

BACKGROUND In Brazil, coffee (Coffea arabica) husks are reused in several ways due to their abundance, including as stall bedding. However, field veterinarians have reported that horses become intoxicated after ingesting the coffee husks that are used as bedding. The objective of this study was to evaluate whether coffee husk consumption causes intoxication in horses. RESULTS Six horses fed c...

OBJECTIVE Surgery for both palmar and axillar hyperhidrosis usually includes the interruption of the sympathetic chain in multiple levels. This study aimed to determine the long-term outcomes associated to video-assisted thoracic sympathotomy (VATS) of T2, T3 and T4 ganglia for these cases. METHODS Analysis of the outcomes obtained from 36 patients regarding the rate of resolution of the symp...

Background: Multiple sclerosis (MS) is an autoimmune disease that causes chronic inflammation of the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs 19–24 nucleotides long, which are differentially expressed in different tissues. The role of miRNAs in MS remains unclear. We assessed miR-10a transcript levels in MS patients during recurrence and two months after relapse. Ma...

BACKGROUND In Olympic combat sports, weight cutting is a common practice aimed to take advantage of competing in weight divisions below the athlete's normal weight. Fluid and food restriction in combination with dehydration (sauna and/or exercise induced profuse sweating) are common weight cut methods. However, the resultant hypohydration could adversely affect health and performance outcomes. ...

SEROTONIN SYNDROME CAUSED BY MOCLOBEMIDE – CLOMIPRAMIN INTERACTION The serotonin syndrome is due to serotoninergic hyperstimulation, which is caused, mostly, by the interaction between a serotoninergic agent and a serotonin-enhancing drug, in particular the monoaminooxidase inhibitors. A male patient, 21 years old, with presenting symptoms and findings as unconsciousness, flushing, diaphoresis,...