OBJECTIVE To measure the cost effectiveness of systematic photographic screening for sight threatening diabetic eye disease compared with existing practice. DESIGN Cost effectiveness analysis. SETTING Liverpool. SUBJECTS A target population of 5000 diabetic patients invited for screening. MAIN OUTCOME MEASURES Cost effectiveness (cost per true positive) of systematic and opportunistic p...

abstract objective: in health economics, one of the important methods of economic evaluation is cost-effectiveness analysis. the usual procedure in this method is to consider effectiveness of disability-adjusted life years (dalys) as a measure criterion. material and methods: this was a cross sectional study of economic assessment type or cost-effectiveness. all over 30 years old population of ...

BACKGROUND Biologics are used for the treatment of inflammatory bowel diseases, Crohn´s disease and ulcerative colitis refractory to conventional treatment. In order to allocate healthcare spending efficiently, costly biologics for inflammatory bowel diseases are an important target for cost-effectiveness analyses. The aim of this study was to systemically review all published literature on the...

INTRODUCTION Chronic asthma is a significant burden for individual sufferers, adversely impacting their quality of working and social life, as well as being a major cost to the National Health Service (NHS). Temperature-controlled laminar airflow (TLA) therapy provides asthma patients at BTS/SIGN step 4/5 an add-on treatment option that is non-invasive and has been shown in clinical studies to ...

To estimate the incremental cost of nosocomial bacteremia according to the causative focus and classified by the antibiotic sensitivity of the microorganism.Patients admitted to Hospital del Mar in Barcelona from 2005 to 2012 were included. We analyzed the total hospital costs of patients with nosocomial bacteremia caused by microorganisms with a high prevalence and, often, with multidrug-resis...

BACKGROUND Heart failure (HF) disease management programs have shown impressive reductions in hospitalizations and mortality, but in studies limited to short time frames and high-risk patient populations. Current guidelines thus only recommend disease management targeted to high-risk patients with HF. METHODS This study applied a new technique to infer the degree to which clinical trials have...

BACKGROUND Detailed information on the cost burden of atrial fibrillation (AF) is limited. To provide an up-to-date estimate of the national cost of AF, we conducted a retrospective, observational cohort study using administrative claims from the MarketScan Commercial and Medicare Supplemental research data bases, 2004 to 2006. METHODS AND RESULTS Patients aged ≥20 years with ≥1 inpatient or ...

OBJECTIVES To determine the incremental net health benefits of dabigatran etexilate 110 mg and 150 mg twice daily and warfarin in patients with non-valvular atrial fibrillation and to estimate the cost effectiveness of dabigatran in the United Kingdom. DESIGN Quantitative benefit-harm and economic analyses using a discrete event simulation model to extrapolate the findings of the RE-LY (Rando...

BACKGROUND To evaluate the various treatments for patients with hormone-refractory prostate cancer with bone metastases using a Markov model. METHODS AND MATERIALS The base case to be evaluated was of a man with hormone-refractory prostate cancer. The evaluated palliative treatments were pain medication only, chemotherapy consisting of mitoxantrone and prednisone, and single- and multifractio...