OBJECTIVE To study the degradation of pyridine and quinoline by two Pseudomonas. METHODS Based on the analysis of 16S rRNA gene sequence homology and the intergenic spacer region sequence, the two isolates were identified. The degradation capability of pyridine and quinoline was determined according to spectrophotometry and Electrospray Ionisation/Mass Spectrometry (ESI/MS). The degrading pla...

Three orthogonal cascade CH functionalization processes are described, based on ruthenium-catalyzed CH alkenylation. 1-Indanones, indeno indenes, and indeno furanones were accessed through cascade pathways by using arylacetophenones as substrates under conditions of catalytic [{Ru(p-cymene)Cl2 }2 ] and stoichiometric Cu(OAc)2 . Each transformation uses CH functionalization methods to form C...

(1)H-NMR and (13)C-NMR assignments of 12-oleanene-3,11-dione (compound 1) were completely described for the first time through conventional 1D NMR and 2D shift-correlated NMR experiments using (1)H-(1)HCOSY, HMQC, HMBC techniques. Based on its NMR data, the assignments of 28-hydroxyolean-12-ene-3,11-dione (compound 2) were partially revised.

Abstract-A novel and efficient method has been developed for the synthesis of pyrano[3,2-c]quinoline-2,5-dione derivatives by the convenient ultrasound-mediated condensation of 4-hydroxyquinolin-2-one with Meldrum’s acid and aldehydes in the presence of a catalytic amount of [HMIm]HSO4 as a green, efficient and reusable acidic ionic liquid medium. The stability of the ionic liquid during the re...

I. INTRODUcrION.......................................... 909 II. JUDICIAL RELUcrANCE TO ApPLY BASIC LEGAL CONCEPTS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 III. THE OIL AND GAS LEASE AND THE LAW OF IMPLIED COVENANTS............................................. 911 A. Professor Merrill's "Oil and Gas Law" Analysis. . . . 911 1. Implying Ob...

In the title compound, C(12)H(13)NO(3), the quinoline ring system is approximately planar with a maximum deviation from the least-squares plane of 0.058 (2) Å. In the crystal, N-H⋯O and O-H⋯O hydrogen bonds link the mol-ecules into chains running along the b-axis direction. The chains also feature π-π inter-actions between pyridine and benzene rings of inversion-related mol-ecules [centroid-cen...

In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra-molecular C-H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol-ecules are linked into infinite chains along...

Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular processes, is highly expressed and active in many tumor cells. A large number of compounds has been developed as inhibitors comprising different backbones. Beside others, structures with an indeno[1,2-b]indole scaffold turned out to be poten...

BACKGROUND AND PURPOSE Acute stroke treatments are underutilized primarily because of delayed hospital arrival. Using a community-based participatory research approach, we explored stroke self-efficacy, knowledge, and perceptions of stroke among a predominately African American population in Flint, Michigan. METHODS In March 2010, a survey was administered to youth and adults after religious ...