Amaryllidaceae is a well-known family for its high alkaloidal content. These alkaloids comprise a unique group of bases that have been found to occur in this family. The Amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not known to occur in any other family of plants. This article reports on the phytochemical investigation...

Leishmaniasis is a parasitic infection that is considered worldwide one of the most important public health problem, affecting more than 12 million people with an estimated number of 2 million new cases occurring annually. Among the compounds isolated from Tabernaemontana catharinensis, coronaridine and voacangine are the indole alkaloids which have antileishmanial activity. In this work, the t...

Phytochemical investigation of the dichloromethane crude extract from bark Ochreinauclea maingayi with aid LCMS/MS-based molecular networking guided isolation and accelerated elucidation known new indole alkaloids. The analysis produces two main clusters, along 41 non-prioritized clusters self-loop nodes. Each cluster has several nodes which depict fractions contained within those An implementa...

Cyanobacteria are recognized producers of toxic or otherwise bioactive metabolite associated, in particular, with so-called "harmful algal blooms" (HABs) and eutrophication of freshwater systems. In the present study, two apparently teratogenic indole alkaloids from a freshwater strain of the widespread cyanobacterial genus, Fischerella (Stigonemataceae), were isolated by bioassay-guided fracti...