OBJECTIVE Several studies have shown an increased risk for neural tube defects associated with prepregnancy maternal obesity. Because few recent studies have examined the relation between maternal prepregnancy obesity and overweight and other birth defects, we explored the relation for several birth defects and compared our findings with those of previous studies. METHODS We conducted a popul...

a 3 month- old boy was admitted with recurrent severe respiratory distress and refractory to therapeutic options. patient underwent a helical multidetector ct examination. axial, coronal and three- dimensional imaging, revealed tracheal bronchus, stenosis, diverticulum and bronchiectasis. in this situation, ct scanning, perfectly 3d imaging is recommend for rule out congenital tracheobronchial ...

Background: Congenital hypothyroidism (CH) is a prevalent disorder, which is associated with several other congenital anomalies, especially cardiac diseases. The present study aimed to determine the prevalence of congenital heart disease (CHD) in the neonates with CH.Methods: This cross-sectional study was conducted on two groups of 79 subjects to compare the type and frequency of congenital ca...

Prune belly syndrome (PBS) is a rare congenital disease presenting characteristic triad of abdominal muscle deficiency, urinary tract abnormality, and cryptorchidism with associated anomalies various systems. We report the anesthetic management an infant PBS no obvious facial deformity in whom we encountered unanticipated difficult airway. Multiple attempts to secure airway different supraglott...

National Registry of Congenital Anomalies (Registro Nacional de Anomalías Congénitas de Argentina, RENAC), a surveillance system for major congenital anomalies (CAs). The RENAC was created in 2009 in response to the growing incidence of CAs as a cause of infant morbidity and mortality. In Argentina, the relative relevance of CAs has increased over the past decades as a cause of infant mortality...

BACKGROUND Although use of efficacious interventions, including antiretrovirals (ARVs), has dramatically reduced the rate of mother-to-child transmission of human immunodeficiency virus, the safety of in utero ARV exposure remains of concern. METHODS Data regarding 1112 infants enrolled in the International Maternal Pediatric Adolescent AIDS Clinical Trials Group protocol P1025 born between 2...