Quality-based assessment of pharmaceuticals obviates the uncertainties concerning their quality, safety and efficacy for regulatory purpose. A method was developed validated quality control cefadroxil or row material analysis. In-silico analysis wasperformedto evaluate bioavailability, toxicity as well asanti-inflammatory potential cefadroxil. The results showed that found linear, accurate, pre...

Teucrium polium, a medicinal plant that belongs to the family Labiatae is widely used in folk medicine as antidiabetic, antibactrial and anti-inflammatory agent. In this study, we evaluated the effect of Teucrium polium on the mouse polymorphonuclear neutrophils. The animals were divided into five groups including four test and one control group, which orally received 50 and 100 mg/kg of aqueou...

results the infusion group had a lower plasma pai-1 level compared to the subcutaneous group at day 7 (11.3 ± 1.6 vs. 16.5 ± 4.2; p = 0.003). the urinary ngal level was lower in the infusion group at day 2 (131.3 ± 11.9 vs. 151.2 ± 20.6; p = 0.014); however, at day 7 the ngal level was decreased in the subcutaneous group as much as the infusion group and there was no significant difference betw...

multiple sclerosis (ms) is a chronic auto-immune disease. most therapeutic strategies for treatment of this disease direct immune modulation and control of inflammatory processes. first-line therapeutic agents showed moderate efficacy and frequent side-effects with moderate efficacy in trials. their parental administration and limited long-term adherence restrict their efficacy compared with se...

The extract of licorice (Glycyrrhiza glabra L.) has been widely used for many centuries in the traditional Chinese medicine as native anti-allergic agent. Glycyrrhizin (GL), a triterpenoid-saponin, extracted from the roots of licorice is the most effective compound for inflammation and allergic diseases in human body. The biological and pharmacological studies revealed that GL possesses many ph...

The dermis is mainly constructed by type I collagen fibers, which provide mechanical strength to the skin building a frame-like structure, and elastic elasticity respond movements of skin. depletion fibers disappearance oxytalan are fiber, characteristic changes in photoaged Prostaglandin E2 (PGE2) one chemical mediators involved inflammation responsible for sunburn. Furthermore, it has been re...

Guduchi is a plant also known as Tinospora cordifolia, having heart shaped leave, an herb of the family Menispermaceae native hot areas Indian subcontinent. In our classical Ayurvedic texts, it indicated to be beneficial in treating various types diseases like skin disorders, different fever, jaundice & gout. claimed have properties anti-oxidant, antihyperglycemic, antihyperlipidemic, hepat...

Abstract: Aim: The goal of this study was to develop colon-targeted nanoparticulate systems the anti-inflammatory agent Quercetin (QU) and evaluate formulation for various parameters that would allow active ingredient be released at a predetermined time location with better pharmaceutical therapeutic properties. Materials Methods: Quercetin-loaded chitosan nanoparticles were formulated purpose ...

HCT116 cells are adherent epithelial derived from the human colorectal carcinoma cell line commonly used to study inflammatory responses in colonic cells. In this study, it was aimed evaluate effects of active anionic H2O8 oxygen solution, which is a very strong antiviral and antimicrobial agent, on HCT-116 cancer line. Cell viability determined by MTT analysis. Antiproliferative activity inves...

The aim of the current study was to investigate influence low-frequency electromagnetic field (LF-EMF) exposure on viability parameters oral mucosa keratinocytes cultured in vitro conditions. effect LF-EMF stimulation cell also specified simultaneous presence lipopolysaccharide (LPS) infectious agent or minocycline (Mino) anti-inflammatory agent. Viability such as early-, late apoptosis and nec...