innovation and sustainable development have been considered fundamental elements in the competitive positioning of companies. the synergies between both concepts, known as eco-innovation, must be considered when designing company policies. the aim of this paper is to analyse which moderating factors determine how innovative companies perform when implementing a sustainable proactive approach...

Cardiac stereotactic body radiation therapy (cSBRT) is an innovative and promising noninvasive treatment option for recurrent, therapy-refractory ventricular tachycardia (VT). Although long term efficacy safety still under evaluation in multicenter studies, it associated with a significant short-term reduction of VT burden ICD shocks.1–3 To date cSBRT neither first line strategy ablation nor pr...

The standard adjuvant therapy for resectable T3 and/or N1-2 rectal cancer is pelvic radiation therapy plus fluorouracil (5-FU)-based chemotherapy. Two randomized intergroup trials, INT 0114 and INT 0144, will help determine the ideal chemotherapeutic agents and their routes of administration in the postoperative setting. The randomized National Surgical Adjuvant Project for Breast and Bowel Can...

Atrial fibrillation is a common arrhythmia in heart failure and a risk factor for stroke. Risk assessment tools can assist clinicians with decision making in the allocation of thromboprophylaxis. This review provides an overview of current validated risk assessment tools for atrial fibrillation and emphasizes the importance of tailoring individual risk and the importance of weighing the benefit...

The boundary between therapy and research may at times be difficult to distinguish, and it is, therefore, important for health care professionals to recognize when a clinical activity should be properly classified as research. Research may be subject to federal regulations which require advance review and approval by an Institutional Review Board (IRB) in order to protect the rights and welfare...

Several reports have shown that acupuncture is an effective method of complementary medicine; however, only a few of these reports have focused on oncological patients treated with radiation therapy. Most of these studies discuss a benefit of acupuncture for side-effect reduction; however, not all could demonstrate significant improvements. Thus, innovative trial designs are necessary to confir...

This article describes an innovative model of couples therapy designed to mitigate marital instability. The authors suggest that combining ongoing couples therapy with a separate relationship-focused group for each partner favorably impacts each person's neuropsychophysiological regulation and their ability to participate in a stable intimate marriage. The neurobiology of attachment theory is s...