OBJECTIVE Understanding the effect of diabetes as well as of alternative treatment strategies on cerebral structure is critical for the development of targeted interventions against accelerated neurodegeneration in type 2 diabetes. We investigated whether diabetes characteristics were associated with spatially specific patterns of brain changes and whether those patterns were affected by intens...

Good blood pressure (BP) control is a central outcome of high-quality diabetes care.1 In the landmark UK Prospective Diabetes Study (UKPDS), intensive BP control led to an absolute risk reduction of 11.2% in diabetes end points over 10 years, an effect 3.5 times greater than intensive blood glucose control.2 Moreover, although intensive glycemic or cholesterol control has an incremental cost-ef...

background: nigella sativa ( n. sativa ) has been used in traditional medicine and several studies have been performed in the last decades to reveal the effects of it on different medical disorders such as diabetes, dyslipidemia, hypertension, and obesity. we evaluated the effects of n. sativa supplementation on lipid profiles, glycemic control, blood pressure (bp), and some anthropometric indi...

background: vitamin d deficiency may play a key role in the development of impaired glucose tolerance, type 2 diabetes mellitus (t2dm), and metabolic syndrome. several studies have shown that vitamin d has an antioxidant property. we aimed to investigate 25?hydroxy vitamin d (25[oh]d) levels in patients with t2dm and in nondiabetic healthy controls and to ascertain the impact of 25(oh)d levels ...

objective diabetes mellitus (dm) as a metabolic disorder is becoming a serious threat of health. in recent years, there has been renewed interest in the treatment against different diseases using medicinal plants. the present randomized clinical trial was carried out to evaluate the efficacy of ziziphus in improving glucose control in women with type 2 diabetes mellitus (t2dm). materials and me...

background: advanced type 2 diabetes mellitus (t2dm) needing insulin therapy is a common disease. previous studies indicate that aloe (aloe vera l.) leaf gel may positively affect the blood glucose and lipid levels in patients with advanced t2dm needing insulin.  objective: evaluation of the efficacy and safety of aloe leaf gel in the treatment of type 2 diabetic patients resistant to oral synt...