The reaction of ground state boron atoms, 11B(2Pj), with allene, H2CCCH2(X1A1), was studied under single collision conditions at a collision energy of 21.5 kJ mol(-1) utilizing the crossed molecular beam technique; the experimental data were combined with electronic structure calculations on the 11BC3H4 potential energy surface. The chemical dynamics were found to be indirect and initiated by a...

Acetonitrile chemical ionization tandem mass spectrometry has recently been shown to be a rapid method for the identification of double-bond position and geometry in methyl esters of conjugated linoleic acids (CLAs); however, the structures of intermediate and diagnostic ions and their mechanisms of formation are not known. A mechanism is proposed here in which the m/z 54 ion, (1-methyleneimino...

Substituted 2, 4- diphenyl quinolines were synthesized by a multicomponent domino reaction of anilines, aldehydes and terminal aryl alkynes. The synthetic pathway involves the formation of an imine, followed by the intermolecular addition of an alkyne to the imine. This intermediate immediately undergoes ring closure and oxidative aromatization. The reaction is catalyzed by natural kaolin, a st...

The RING-in-between-RING (RBR) E3s are a curious family of ubiquitin E3-ligases, whose mechanism of action is unusual in several ways. Their activities are auto-inhibited, causing a requirement for activation by protein-protein interactions or posttranslational modifications. They catalyse ubiquitin conjugation by a concerted RING/HECT-like mechanism in which the RING1 domain facilitates E2-dis...

We present a full account of our synthetic studies on the racemic DEFGH-ring moiety of physalins, featuring domino ring transformation of a tricyclic key intermediate. We also report the results of a detailed mechanistic examination of the domino ring transformation, as well as a reoptimization of the 2,3-Wittig rearrangement and methylation steps. Furthermore, we have newly established a metho...

A base-promoted formal arylation of benzo[d]oxazoles with acyl chloride was achieved in moderate to good yields. This reaction was triggered by the N-acylation of oxazole to form an iminium intermediate. Then, the addition of H2O to the iminium formed the hemiacetal intermediate. After the sequential ring-opening, extrusion of CO, the ring closure, the dehydration delivered the formal arylation...

The reactivity of a,w-diphenylalkanes (1 I n I 4) toward Me3C+ ions has been investigated with the radiolytic technique at 720 Torr, at temperatures of 47 and 120 “C. The intramolecular isotopic discrimination of Me3C+, favoring attack at the unlabeled ring of C6Hs(CH2)2C6Ds by a factor of 1.5 at 120 “C, contrasts with the lack of intermolecular isotopic discrimination, reflected by the same re...

A large number of aromatic substances can be found in so-called coal tar (containing >10,000 individual compounds), which is a mixture heavy liquid fractions (dense viscous black liquor, tended to solidification) obtained after the pyrolysis (solid product—coke, gas products, and light products are also produced during process). Volatile monocyclic hydrocarbons, naturally occurring tar, expl...

Similar to propargylic carboxylates and sulphides, 3-propargylindoles undergo 1,2-indole migrations under cationic gold(I) catalysis. The intermediate Au-carbenoid complex may evolve through different pathways depending on the substituents at the propargylic and terminal positions of the alkyne moiety. Thus, 3-indenylindole derivatives were easily obtained through formal iso-Nazarov or Nazarov ...

Let $R$ be a commutative Noetherian ring. We prove that  over a local ring $R$ every finitely generated $R$-module $M$ of finite Gorenstein projective dimension has a Gorenstein projective cover$varphi:C rightarrow M$ such that $C$ is finitely generated and the projective dimension of $Kervarphi$ is finite and $varphi$ is surjective.