Phagocytosis of shed photoreceptor outer segments (POSs) by retinal pigment epithelial (RPE) cells is critical to retinal homeostasis and shares many conserved signaling pathways with other phagocytes, including extrinsic regulations. Phagocytotic ligands are the key to cargo recognition, engulfment initiation, and activity regulation. In this study, we identified intracellular protein ATP-bind...

Closure of carpels or angiospermy, a key developmental innovation, has been accomplished through different ontogenic routes among the flowering plants. The mechanism of angiospermy produces structural novelties in the gynoecium, which in turn affects the progamic phase. In this paper, we present the structural details of the gynoecium and functional attributes of the progamic phase of Hippophae...

The present study addresses gaps in the literature related to theory development for young men who have sex with men (YMSM) sexual practices through the application and modification of Social Action Theory. Data come from the Healthy Young Men study (N = 526), which longitudinally tracked a diverse cohort of YMSM ages 18-24 to characterize risk and protective factors associated with drug use an...

When children experience habitual peer difficulties, adults often remind them that many people care about them. How do such reminders of support impact children's emotional responses to acute experiences of peer disapproval? Intuitively, support reminders would exert compensatory effects attenuating the emotional impact of acute disapproval. Theory suggests, however, that support reminders migh...

BACKGROUND In most countries, suicide is second or third leading cause of death in youth. Suicidal tendencies among youth have been the subject of extensive research. Reports of increased rate of suicide attempts in the past few decades indicate that this phenomenon has not been fully understood. AIM The aim of this study was to better understand the phenomenon of adolescent suicide behavior ...

objectives: psychiatric stigma refers to systemic and internalized stereotypical negative attitudes against individual with mental illness. this article describes the level of self stigma, stereotype endorsement and perceived discrimination experienced by patients with bipolar-i disorder in tehran. methods: data were collected from a total of 126 patients with bipolar-i disorder who responded t...

Background Research on adults points to personality as a crucial determinant of well-being. The present study investigates the question of personality's relation to well-being and psychosocial adjustment in adolescence. Methods We assessed the role of temperament and character (Temperament and Character Inventory, TCI-125), on psychological well-being (PWB; Psychological Well-Being scales), s...