Today, digital recording of live lectures is a common practice at many universities. This article provides an historical overview of this idea, from the first approaches starting 40 years ago to present-day systems and questions still subject of research. Zusammenfassung Die digitale Aufzeichnung von Vorlesungen ist heute an Hochschulen Alltag. Der Beitrag beschreibt die 40-jährige Entwicklung ...

In the preceding paper (Dallos, P. (1985) J. Neurosci. 5: 1591-1608) some fundamental properties of cochlear inner and outer hair cells were considered. On the basis of intracellular recording from the low frequency region of the guinea pig cochlea, such measures as membrane potentials, the dependence of AC and DC receptor potential magnitude on stimulus level and frequency, and tuning characte...

The biological information extracted from various excitable tissues can be obtained by intracellular as well as by extra-cellular recordings, the latest one being easier and noninvasive method with many applications in medicine testing. Electrophysiological recording of the eye excitability is analyzed in the following computational study dedicated to the diagnosis of the type of dynamics gover...

introduction: the ionic currents show nonlinear behavior and electrical stimuli can influence their activation and inactivation kinetics. the time constant of depolarizing or hyperpolarizing current pulses has an important role in the firing behavior of neurons. in the present study, the effects of quasitrpezoidal command potentials on l-type calcium channel of somata of f1 neuron in helix aspe...

  While the effect of changes of stimulus waveform (quasitrapezoidal and rectangular current pulses) on nerve activation is clear, but there is no evidence on the effect of quasitrapezoidal pulses on ionic currents of cellular membrane. In the present study, the effect of depolarizing quasi-trapezoidal current pulses, in comparison with that of depolarizing rectangular current pulses, on firing...

In light of the proliferation of channels and receptors that are being cloned from the mammalian CNS it is a major challenge to understand their different roles in signalling and synaptic transmission within the brain. The patch-clamp technique developed by Neher, Sakmann and co-workers 1-3 has allowed successful studies of ionic currents and the underlying single-channel activity in the small ...

An early consequence of brain energy deprivation is an increase in the frequency of spontaneous inhibitory and excitatory postsynaptic currents (sIPSCs and sEPSCs), which may disrupt neural information processing. This increase in spontaneous transmitter release has been reported to occur in calcium-free solution and has been attributed either to calcium release from internal stores or to a dir...