Atomic force microscopy (AFM, also called scanning force microscopy) is proving to be a useful technique for imaging DNA. Thus it is important to push the limits of AFM imaging in order to explore both what types of DNA can be reliably imaged and identified and also what substrates and methods of sample preparation are suitable. The following advances in AFM of DNA are presented here. (i) DNA m...

Ni6(N2H4)6(SO4)4(OH)2(H2O)8](SO4)(H2O)10 complex was prepared according to literature report. The reaction between aforementioned complex via sodium alkoxides as a reactants, were carried out in the solid state. The [Ni6(N2H4)6(SO4)4(OH)2(H2O)8](SO4)(H2O)10 undergoes an intramolecular two electrons oxidation-reduction reaction at room temperature and metallic nickel nanoparticles (Ni1-Ni5) was ...

Along with the intramolecular C–H insertion reactions by carbenoids, intramolecular N–H insertion reactions of α-diazocarbonyl substrates catalyzed by metal complex have received considerable attention in recent years. This type of insertion reaction has been shown to be a mild and efficient route to 4-, 5-, and 6-membered aza rings. A frequently cited example of this powerful approach is the M...

the n-(2-benzoyl-phenyl) oxalyl derivatives are important models for studying of three-centered intramolecular hydrogen bonding in organic molecules. the quantum theoretical calculations for two crystal structures of n-(2-benzoyl-phenyl) oxalyl (compounds i and ii) were performed by density functional theory (b3lyp method and 6-311+g* basis set). from the optimized structures, geometric paramet...

We demonstrate a unique mechano-luminochromic (MLC) effect of an aggregation-induced emission (AIE)-active luminogen (AIEgen), DTPE-TB, which is characterized by the evidently changed intensity but unimpressively shifted colors molecular solid. This behavior termed mechanofluoro enhancement (MFE), quite distinct from commonly reported AIEgens with MLC property. The MFE originates special design...

A new and imaginative technique for the synthesis of substituted pyranoquinoline via Algar Flyn Oyamanda oxidation cyclization approach has been achieved by hydrogen peroxide and sodium hydroxide catalyzed of quinoline chalcone with intramolecular cyclization to formed pyranoquinoline. In this reaction, two new C-C bonds were formed in a one step with high atom economy. The possible reaction pa...

There are several facets to our interest in temperature, solvent, and isotope effects on NMR chemical shifts. Excepting molecular beam studies, the application of NMR to the elucidation of molecular structure and mechanisms of molecular reactions nearly always involves observations of molecules in some environment. Before NMR can be used to obtain structural and mechanistic information unambigu...

Escherichia coli chromosome DNA was observed previously to consist of subunits of Archimedean spirallike supercoiling. How do cells build such a DNA structure remains unknown. In the present study, atomic force microscopy (AFM) images showed that supercoiled pBR322 DNA forms a spiral structure upon intercalation with 0.5 μg/ml ethidium bromide (EB), which used to be considered as zero superheli...