(TDDS), additionally called ‘ Transdermal patches,’ square measures dose form design to deliver a The human skin is readily accessible surface for drug delivery. Drug Delivery Systems therapeutically effective quantity of across patients skin. In order therapeutics agents through the systemic effect, comprehensive morphological , biophysical and physicochemical properties are be considered. del...

nowadays, environment-sensitive smart drug delivery systems have found diverse applications in pharmaceutical science and technology. these systems can respond to the environment stimuli such as temperature, pressure, ph, light, electrical and magnetical fields and etc. they can release the proper amount of drug in human body. among these systems, special attention and much research works have ...

INTRODUCTION As healthcare budgets continue to contract, there is increased payer scrutiny on the use of implantable intrathecal drug-infusion devices. This study utilizes claims data to evaluate the economic effects of intrathecal drug delivery (IDD) based on health services utilization and costs of care before and after implantation. METHODS We performed a retrospective database study invol...

drug-in-adhesive transdermal drug delivery systems  )tddss) containing stimulants, termed as energetic substances, such as caffeine and pantothenic acid, were studied. caffeine is a white crystalline substance and a stimulant to central nervous system. in humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. pantothenic acid, al...

oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...

BACKGROUND The neuroprotective role of minocycline in the treatment of brachial plexus injury is controversial. OBJECTIVE To study the neuroprotective effect of minocycline via different routes in adult Sprague Dawley rats with brachial plexus injury. METHODS The C7 nerve roots of the animals were avulsed via an anterior extravertebral approach. Traction force was used to transect the ventr...