Intravascular large B-cell lymphoma (IVLBCL) is an aggressive non-Hodgkin's lymphoma which can present with B symptoms, rash, and neurological deterioration. Up to 10% of cases of IVLBCL are associated with other hematological neoplasms, including this extremely rare presentation of IVLBCL as Richter's transformation in chronic lymphocytic leukemia.

Intravascular large B-cell lymphoma (IVLBL) is a rare subtype of diffuse large B-cell lymphoma that resides in the lumen of blood vessels. Patients typically present with nonspecific findings, particularly bizarre neurologic symptoms, fever, and skin lesions. A woman presented with shortness of breath and a chest CT scan showed diffuse interstitial thickening and ground glass opacities suggesti...

A 77-year-old woman was referred with renal impairment—serum creatinine 230 mmol/L (2.61 mg/dL) and proteinuria 2.14 g/day. The past medical history included hypertension, sicca symptoms and osteoarthritis. Her medications included amlodipine 5 mg od, omeprazole 20 mg od and prednisolone 10 mg od. Systematic enquiry revealed lethargy and 6 kg weight loss over 6 months. Examination was unremarka...

Intravascular lymphoma (IVL) is a rare type of extra-nodal lymphoma with an aggressive clinical course characterized by proliferation of large lymphoma cells within the lumina of small vessels. Diagnosis of IVL is extremely difficult because of its varied clinical symptoms and the absence of lymphadenopathy, which requires histological confirmation. We report a case of a patient with Mono-Neuri...

Intravascular lymphoma is a very rare form of large B-cell non-Hodgkin's lymphoma which is characterized by selective growth of lymphoma cells within the lumina of small blood vessels. We report a 64-year-old woman visited hospital because of persistent cough, intermittent high fever as high as 38.7 °C and occasional shortness of breath. Her chest CT showed left upper lobe pneumonia and tubercu...

A 55-year-old man presented with flaccid paraparesis. Immunologic and serologic tests were unrevealing. Nuclear magnetic resonance revealed brain and spinal ischemic lesions suggestive of isolated central nervous system vasculitis. Treatment with cyclophosphamide and steroids was initiated, resulting in clinical improvement. However, 1 month later, the patient acutely developed altered mental s...

A 59-year-old man presented with acalculous cholecystitis and hepatomegaly. Routine laboratory tests were remarkable for thrombocytopenia (125 109/L), alanine aminotransferase 95 U/L, aspartate aminotransferase 760 U/L, alkaline phosphatase 223 U/L, and lactate dehydrogenase 3755 U/L. A peripheral smear showed morphologically normal red blood cells and large atypical lymphoid cells (panel A and...

We report an incidental case of intravascular large B-cell lymphoma (IVLBCL) coexisting with an ovarian carcinoma in a 76-year-old woman. She visited our hospital with difficulty in defecation. Magnetic resonance imaging and computerized tomography scan revealed a solid and cystic mass probably arising from the left ovary. Gross examination of the tumor obtained by an exploratory surgery showed...

most bladder tumors are epithelial in origin. nonepithelial cancers are rarely located in the bladder. sarcomas are the most common malignancies among nonepithelial cancers. primary bladder lymphoma is rare and mostly low grade. here, we have reported a case of diffuse large cell lymphoma of the bladder. the patient, a 64-year-old man, had urinary frequency for 18 months. abdominal sonography i...