A single intravenous dose of cefpirome, 50 mg/kg, was administered to 15 children with bacterial meningitis 24 to 48 h after initiation of standard antibiotic and steroid therapy. Cefpirome concentrations in serum and cerebrospinal fluid were determined at selected time intervals. The mean (standard deviation) peak concentration in cerebrospinal fluid (n = 5) was 10.8 (7.8) microg/ml. Drug conc...

AIM To report the successful recovery of few dairy cattle from botulism in response to a modified therapeutic strategy. MATERIALS AND METHODS Seventy four naturally-occurring clinical cases of bovine botulism encountered during the period of 2012-2014 which were confirmed by mouse lethality test became material for this study. Affected animals were made into three groups based on the treatmen...

conclusions: the major barriers for thrombolytic therapy for patients with ais in this setting were delays in the provision of in-hospital services, like initial patient assessment, ct scans or laboratory studies. these results were in contrast with previous reports. background: intravenous thrombolysis is an approved treatment method for patients with acute ischemic stroke (ais) and is recomme...

conclusions in critically ill patients, the symptoms of hypophosphatemia may not be apparent, but clinicians should be vigilant about this complication during therapy. in cases of severe symptoms (e.g., cardiopulmonary distress, anemia and thrombocytopenia, or rhabdomyolysis), phosphate therapy under close surveillance is warranted. introduction although asymptomatic hypophosphatemia is a commo...

conclusions the early signs and symptoms of iscls may be subtle; therefore the diagnosis can easily be missed and prompt treatment of the syndrome may be postponed. thus, the clinician must consider iscls in differential diagnosis in cases of hypotension, hemoconcentration, and hypoalbuminemia. case presentation we present a 58-year-old female who presented with peripheral edema, leg pain, and ...

Rehydration strategies in children with severe acute malnutrition Background: (SAM) and severe dehydration are extremely cautious. The World Health Organization (WHO) SAM guidelines advise strongly against intravenous fluids unless the child is shocked or severely dehydrated and unable to tolerate oral fluids. Otherwise, guidelines recommend oral or nasogastric rehydration using low sodium oral...