Recently, nitric oxide (NO) has been thought to be a neuronal messenger to evoke penile erection. NO synthase (NOS)-containing nerve fibers were identified and localized in human penile tissue, but detail distribution of NOS-containing nerve fibers in the human penis was unclear. In the present study we examined their distribution using histochemical staining of NADPH diaphorase (ND), which is ...

Development of the facial nerve was studied in normal chicken embryos and after surgical disruption of ingrowing sensory facial nerve fibers at 38-72 h of incubation. Disruption of facial nerve fibers by otocyst removal often induced a rostral deviation of the facial nerve and ganglion to the level of the trigeminal ganglion. Cell bodies of the geniculate ganglion trailed their deviating neurit...

Injury of limb nerves leading to neuropathic pain mostly affects deep somatic nerves including muscle nerves. Here, we investigated the functional properties of injured afferent fibers innervating the lateral gastrocnemius-soleus muscle 4-13 h [time period (TP) I] and 4-7 days (TP II) after nerve crush in anesthetized rats using neurophysiological recordings from either the sciatic nerve (165 A...

This study assesses the effects of age on the composition of the anterior commissure of the rhesus monkey. The anterior commissures of nine young (5-10 years), five middle-aged (15-20 years), and eight old (25-35 years) monkeys were examined by light and electron microscopy. In all, 90-95% of the nerve fibers in the anterior commissure are myelinated. With age, the structure of the myelin sheat...

this study was conducted on 48 specimens of rectus abdominis muscles for recognition and definition of passage and ramification of lower intercostal nerves. the main results of this study are as follows: 1- the seventh and eight intercostal nerves penetrated to posterior layer of the rectus sheath while other intercostal nerves perforated to dorsal layer of internal oblique abdominis aponeurosi...

Considerable information on the submicroscopic structure of nerve fibers has been obtained from polarization opitical analyses and x-ray diffraction studies, but such methods do not allow direct visualization of details lying beyond the light microscope's resolution . Successful application of the electron microscope to this problem with its increase in resolving power has made possible an exte...

Progressive loss of pain perception and cutaneous nerve fibers are frequently observed in diabetic patients. We evaluated the feasibility of using thy1-YFP mice that express the yellowish-green fluorescent protein (YFP) in all of their sensory/motor neurons for noninvasive monitoring of cutaneous nerve fiber loss during diabetes. Fluorescent fibers in skin sections from the leg of thy1-YFP mice...

PURPOSE The corneal innervation, mainly analyzed in light microscopical studies, has been described as radially oriented stromal nerve bundles that ramify as leashes in the subbasal plexus. The current study aims to determine the orientation, the size, and the postmortem changes of the nerve fibers in the subbasal plexus of the human cornea. METHODS Before processing for light and electron mi...

BACKGROUND So far, there exists no golden standard for the treatment of arthrofibrosis (AF) following total knee arthroplasty (TKA). Although pain is a hallmark of AF, nociceptive nerve fibers have never been investigated in affected joint tissue. METHODS A total of 24 patients with osteoarthritis (OA) of the knee (n = 12) and post-TKA AF of the knee (n = 12) were included. Along evaluation o...