Kankkunen, T., 2002. Controlled transdermal drug delivery by iontophoresis and ionexchange fiber. Dissertationes Biocentri Viikki Universitatis Helsingiensis 17/2002, pp. 57 ISBN 952-10-0313-8 (print) ISBN 952-10-0314-6 (pdf) ISSN 1239-9469 A common aim in the development of new transdermal devices is the controlled delivery of drugs, so that the rate of drug input into the blood stream is pred...

Studies of ion transport pathophysiology in hematological disorders and tests of possible new therapeutic agents for these disorders have been carried out in various mouse models because of close functional similarities between mouse and human red cells. We have explored strain-specific differences in erythrocyte membrane physiology in 10 inbred mouse strains by determining erythrocyte contents...

The main goal of this study was to prepare and characterize ion exchangers on nanofibrous polystyrene matrix. Starting nanofibers were sulfonated and crosslinked at the same time by sulfuric acid. Strongly acidic cation exchanger was obtained in such a way. Anion exchanger was prepared by reaction of ethylene diamine with sulfochlorides on nanofibers acquired from sulfogroups. The polymer matri...

CLC-ec1 is a prokaryotic CLC-type Cl(-)/H+ exchange transporter. Little is known about the mechanism of H+ coupling to Cl-. A critical glutamate residue, E148, was previously shown to be required for Cl(-)/H+ exchange by mediating proton transfer between the protein and the extracellular solution. To test whether an analogous H+ acceptor exists near the intracellular side of the protein, we per...

An uptake of zinc (Zn), copper (Cu), and lead (Pb) from aqueous solutions by ion exchange on natural zeolitic tuff has been studied. The Croatian zeolite clinoptilolite from the Donje Jesenje deposit has been used as a natural ion exchanger. The efficiency of removal is higher for Pb and Cu than for Zn ions. Measured concentrations of Si in the liquid phase identify the detachment of the alumin...

Electrode potential measurements have been applied to study electrical characteristics like transport numbers, permselectivity & fixed charge density of ion-exchange membranes. Membrane potential measurements were made across zirconium phosphotungstate cation-exchange membrane maintained at 27◦C, using halide salts of alkali & alkaline earth metals as electrolytes. The effect of concentration o...