EMBO reports (2009) 10, 689–693. doi:10.1038/embor.2009.136 Introduction At the recent Keystone Symposium on Chromatin Dynamics and Higher Order Organization, an emerging and expanded view of the chromatin landscape was apparent. Many reports connected the organization of individual nucleosomes and histone-modification domains with the spatial co-localization of genes and regulatory elements in...

BACKGROUND Assessing growth is a useful tool for defining health and nutritional status of children. The objective of this study was to construct growth reference curves of Iranian infants and children (0-6 years old) and compare them with previous and international references. METHODS Weight, height or length of 2107 Iranian infants and children aged 0-6 years old were measured using a cross...

BACKGROUND Cytochrome P450 2C19 (CYP2C19) is important in metabolism of wide range of drugs. CYP2C19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (URM). Distribution of this variant allele has not been well studied worldwide. The aim of present study was to investigate allele and genotype frequencies of CYP2C19*17 in ...

The Gilaki and Mazandarani occupy the South Caspian region of Iran and speak languages belonging to the North-Western branch of Iranian languages . It has been suggested that their ancestors came from the Caucasus region, perhaps displacing an earlier group in the South Caspian . Linguistic evidence supports this scenario, in that the Gilaki and Mazandarani languages (but not other Iranian lang...