Zinc (Zn) is abundantly enriched in sub-retinal pigment epithelial (RPE) deposits, the hallmarks of age-related macular degeneration (AMD), and is thought to play a role in the formation of these deposits. However, it is not known whether Zn is the only metal relevant for sub-RPE deposit formation. Because of their involvement in the pathogenesis of AMD, we determined the concentration and dist...

Parking Services [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gu...

Parking Services [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gu...

Parking Permits [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gue...

Parking Services [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gu...

Parking Services [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gu...

Parking Services [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gu...

Parking Permits [1] Parking permits are required to park on campus. Parking permits can be purchased online. Campus Map [2] The Campus map allows you to search for a location on campus by selecting a building or selecting a department name. Identification (ID) card Please visit Human Resources, 5th floor, South Tower, University Centre, to complete an ID application form. Your University of Gue...

Ferroportin (FPN) mediates iron export from cells; FPN mutations are associated with the iron overloading disorder hemochromatosis. Previously, we found that the A77D, V162del, and G490D mutations inhibited FPN activity, but that other disease-associated FPN variants retained full iron export capability. The peptide hormone hepcidin inhibits FPN as part of a homeostatic negative feedback loop. ...