A new design of an immunosensor for viral molecules based on the ISFET nanoscale structure has been proposed. Physical processes take place inimmunosensor are modeled. The effect modulation surface potential interface between a semiconductor depleted layer (channel) and dielectric during interaction immobilization was used. Analytical expression source-drain current as function virus types conc...

Novel applications of online pH determinations at temperatures from -35 °C to 130 °C in technical and biological media, which are all but ideal aqueous solutions, require new approaches to pH monitoring. The glass electrode, introduced nearly hundred years ago, and chemical sensors based on field effect transistors (ISFET) show specific drawbacks with respect to handling and long-time stability...

Rapid acid-base titrations can be performed at the surface of a noble-metal electrode with coulometrically generated ions. An ISFET is used as an indicator electrode to detect the equivalence point in the resulting titration curve. The time needed to reach the equivalence point is typically 0.5 to 10 s for acid/base concentrations ranging from 0.5 x lop3 to 20 x lop3 mol 1 -I. A model is presen...

This paper reports a development of microfluidic devices integrating an ion selective-field effect transistor (ISFET) sensor with a tantalum pentoxide as a sensing surface to detect protons. To attain high sensitivity in flow injection analysis, a novel on-line preconcentration of ionic analytes was demonstrated by integrating a pair of metal electrodes on a microchannel. In our proposed method...