BACKGROUND The aim of this study was to identify corresponding body mass index (BMI) and waist circumference cut-offs for equivalent levels of insulin sensitivity in a Middle Eastern immigrant population compared with native Swedes. METHODS Citizens of Malmö, Sweden aged 30 to 75 years, who were born in Iraq or Sweden, were in 2010-2012 invited to participate in a health examination including...

OBJECTIVES To investigate the associations between cytokines and insulin sensitivity in Swedish residents born in Iraq and Swedish residents born in Sweden. DESIGN Cross-sectional study. SETTINGS Iraqi and Swedish origin residents of Rosengård area of Malmö, aged 45-65 years, were randomly selected from the census register. PARTICIPANTS/METHODS 194 (Iraqi, n=107; Swedish, n=87) participan...

STUDY OBJECTIVES Determine effects of low-dose estradiol and low-dose venlafaxine on self-reported sleep measures in menopausal women with hot flashes. DESIGN 3-arm double-blind randomized trial. Participants assigned in a 2:2:3 ratio to 17β estradiol 0.5 mg/day (n = 97), venlafaxine XR 75 mg/day (n = 96), or placebo (n = 146) for 8 weeks. SETTING Academic research centers. PARTICIPANTS 3...

OBJECTIVE Diabetic nephropathy (DN) is a major cause of mortality in type 1 diabetes. Reduced insulin sensitivity is a well-documented component of type 1 diabetes. We hypothesized that baseline insulin sensitivity would predict development of DN over 6 years. RESEARCH DESIGN AND METHODS We assessed the relationship between insulin sensitivity at baseline and development of early phenotypes o...

Although the extent of enzymatically estimated infarct size appears to be an important determinant of morbidity and mortality early after infarction, its influences on long-term survival and late ventricular dysrhythmia have not yet been characterized. Accordingly, we prospectively studied 173 patients younger than 66 years of age without evidence of prior myocardial infarction, who survived ac...

Graph energy is defined to be the p -norm of adjacency matrix associated graph for = 1 elaborated as sum absolute eigenvalues matrix. The graph’s spectral radius represents matrix’s largest eigenvalue. Applications energies and radii can found in both molecular computing computer science. On similar lines, Inverse Sum Indeg, ( ISI ) energies, constructed. This article’s main focus generalized s...

Objectives Our goal is to validate and to verify the reliability of the French and English versions of the Insomnia Severity Index (ISI) in Lebanese adolescents. Study design A cross-sectional study was implemented. Methods 104 Lebanese students aged between 14 and 19 years participated in the study. The English version of the questionnaire was distributed to English-speaking students and t...

OBJECTIVE Insulin resistance is a risk factor for cardiovascular and noncardiovascular diseases. Impaired kidney function is linked with insulin resistance and may affect relationships of insulin resistance with health outcomes. RESEARCH DESIGN AND METHODS We performed a cohort study of 3,138 Cardiovascular Health Study participants (age ≥ 65 years) without diabetes. Insulin sensitivity index...

AIMS To determine the minimum number of calibrant plasmas required to assign an accurate System International Sensitivity Index (ISI). METHODS Eighteen lyophilised adsorbed and eight frozen coumarin plasmas were despatched to 57 participating laboratories. Each centre determined the prothrombin time of all of the plasmas using their routine system of coagulometer and thromboplastin reagent an...

Obesity has been associated with dysfunctional postprandial adipose tissue blood flow (ATBF), but it has also been recognized that the interindividual response is highly variable. The present work aimed at characterizing this variability. Fifteen subjects were given 75 g oral glucose, and abdominal subcutaneous ATBF was monitored by the (133)Xe washout method. Determinants of insulin sensitivit...