Owing to the proximity of the pancreas and duodenum, the pathogenesis, diagnosis, and management of pancreaticoduodenal injury, while being distinct are all still interrelated. While management of pancreatic injury is related to injury classification, which may vary greatly from non-surgical intervention, operative therapy, or pancreaticoduodenectomy (PD), identification of pancreatic duct inju...

The aim of the present study was to evaluate acute blunt pancreatic injury using contrast-enhanced ultrasonography (CEUS) in comparison with contrast-enhanced computed tomography (CECT). Superficial and deep lesions were established by blunt pancreatic injury in 40 Chinese Guangxi Bama miniature pigs. Conventional ultrasound (US), CEUS and CECT were performed to detect traumatic lesions in the ...

PURPOSE This study aimed to investigate the therapeutic potential of hydrogen-rich saline on pancreatic ischemia/reperfusion (I/R) injury in rats. METHODS Eighty heterotopic pancreas transplantations (HPT) were performed in syngenic rats. The receptors were randomized blindly into the following three groups: the HPT group and two groups that underwent transplantation and administration of hyd...

Isolated pancreatic hydatid cysts are a rare parasitic disease even in endemic areas. It is difficult to discriminate primary pancreatic hydatid cysts from other cystic and solid lesions of the pancreas. This is a case report of an incidental isolated pancreatic hydatid cyst. A heterogeneous cystic lesion in the body of the pancreas was identified on magnetic resonance imaging of a patient prev...

Physiological calcium (Ca(2+)) signals within the pancreatic acinar cell regulate enzyme secretion, whereas aberrant Ca(2+) signals are associated with acinar cell injury. We have previously identified the ryanodine receptor (RyR), a Ca(2+) release channel on the endoplasmic reticulum, as a modulator of these pathological signals. In the present study, we establish that the RyR is expressed in ...

The mechanism by which alcohol injures the pancreas remains unknown. Recent investigations suggest a role for fatty acid ethyl ester (FAEE), a nonoxidative metabolite of ethanol, in the pathogenesis of alcohol pancreatitis. In this study, we characterized ethanol-induced injury in rats and evaluated the contribution of oxidative and nonoxidative ethanol metabolites in this form of acute pancrea...

isolated scaphoid dislocation is a rare injury of the wrist. to our knowledger, only 22 cases of isolated scaphoid dislocation have been reported in enghish-language literature and we could find only one case with pure radial dislocation. we present a 34-year-old man with isolated pure radial scaphoid dislocation that was treated by open reduction and repair of the scapholunate ligament and pin...

This study expanded upon a previous study in mice reporting a link between exenatide treatment and exocrine pancreatic injury by demonstrating temporal and dose responses and providing an initial mechanistic hypothesis. The design of the present study included varying lengths of exenatide exposure (3, 6 weeks to 12 weeks) at multiple concentrations (3, 10, or 30 µg/kg) with multiple endpoints (...

CONTEXT Pancreatic abscesses are uncommon and usually occur in the setting of pancreatitis. Isolated pyogenic pancreatic abscesses without any precipitating events are extremely rare. CASE REPORT A 72-year-old man with a two month history of non-specific abdominal discomfort, distension, anorexia and weight loss was admitted for further evaluation. A computer tomography scan showed a lesion o...