BACKGROUND Pruritus affects the quality of life (QoL) in the patients. However, little is known of the impacts of itching on the QoL in the literature. OBJECTIVE In this study, a questionnaire eliciting specific responses about pruritus was used to determine the effect of itching and its severity on QoL in chronic pruritic patients. METHODS One hundred ten adult patients with chronic prurit...

OBJECTIVE To determine whether the extent, distribution, and duration of vitiligo are associated with impairment of specific aspects of quality of life. DESIGN A prospective questionnaire-based study of 1541 adults with vitiligo. SETTING Online questionnaire. MAIN OUTCOME MEASURES Affected body surface area (BSA), distribution and duration of vitiligo, associated symptoms, and quality of ...

OBJECTIVES To evaluate the efficacy of adding Coblation-assisted inferior turbinoplasty to a medical treatment regimen for symptoms associated with hypertrophic inferior turbinates. STUDY DESIGN/SETTING Prospective, open-label, non-randomized trial with outpatient treatment. Patients were assigned to treatment groups in order of enrolment into the study. SUBJECTS AND METHODS From June 2007 ...

Abstract Background and Aims Chronic kidney disease–associated pruritus (CKD-aP) is a common highly distressing condition in patients undergoing hemodialysis (HD). CKD-aP associated with sleep disturbances, significant quality-of-life (QoL) impairment, increased morbidity mortality. Difelikefalin (DFK) selective kappa opioid receptor agonist development for that has minimal central nervous syst...

Objectives  We report on a patient suffering from intractable itching secondary to intrahepatic cholestasis of pregnancy (ICP) unresponsive to conventional medical therapies. She was started on a regimen of therapeutic plasma exchange (TPE), which is often efficacious in relieving patient's itching from all causes of cholestasis, including ICP. Methods  We performed a retrospective review of a ...

Background Post-herpetic itch (PHI) is a neuropathic itch syndrome following herpes zoster. It has been reported that PHI is occasionally sufficiently severe to compromise patients' quality of life and frequently refractory to treatment. Here, we present a case of severe chronic PHI successfully treated with supraorbital nerve block using a high concentration of tetracaine dissolved in bupivaca...

AIM To determine whether use of a topical, nonsteroidal, anti-inflammatory, and anti-itching formula was able to preserve the absence of symptoms, mainly itching and burning, induced by an earlier and relatively short treatment with topical steroids in women diagnosed with vulvar dermatitis or lichen simplex. METHODS Ninety-six subjects (36 with contact dermatitis, 29 with allergic dermatitis...