Benchmarking surveillance systems requires realistic simulations of disease outbreaks. However, obtaining these data in sufficient quantity, with a realistic shape and covering a sufficient range of agents, size and duration, is known to be very difficult. The dataset of outbreak signals generated should reflect the likely distribution of authentic situations faced by the surveillance system, i...

Elotuzumab, targeting signaling lymphocytic activation molecule family 7 (SLAMF7), has been approved in combination with lenalidomide and dexamethasone (ELd) for relapsed/refractory multiple myeloma (MM) based on the findings of the phase III randomized trial ELOQUENT-2 (NCT01239797). Four-year follow-up analyses of ELOQUENT-2 have demonstrated that progression-free survival was 21% in ELd vers...

E-learning merupakan peralihan proses pembelajaran dari tatap muka langsung di dalam kelas menjadi berbasis digital. Dalam bidang pendidikan, e-learning sebagai kemajuan teknologi informasi telah dimanfaatan sarana perguruan tinggi karena dirasakan mampu meningkatkan kegiatan akademik khususnya agar lebih efektif dan efisien. Ketergantungan terhadap TI semakin meningkat untuk mencapai tujuan or...

Group-based Decision and Knowledge Support Systems have the potential to assist Information Technology Service Managers make sound decisions. We use narrative enquiry and reflective processes to review two recent projects that designed decision support tools for IT Service Management. The Software Mediated Process Assessment project includes a group decision support system to enable the selecti...

This paper presents the construction of a maturity model for analyzing the strategic IT service management process of internal IT service provider’s in early growth stages. This model is presented as an alternative tool for improving the understanding, from an IT service management perspective, of: (i) the strategic IT processes/practices situation in an IT organization, and (ii) facilitate the...

This article consinders the problem of designing sustainable development tools for manager organizations hoursing and communal service. The applying process approach to management apartment buildings is discussed in example system relationships between owners premises companies. main business processes a managing organization company are identified, which make up pool CRM as tool customer focus...

The paradigm of service-oriented architectures (SOA) is by now accepted for application integration and in widespread use. As an underlying key-technology of cloud computing and because of unresolved issues during operation and maintenance it remains a hot topic. SOA encapsulates business functionality in services, combining aspects from both the business and infrastructure level. The reuse of ...

Service and service systems concepts are fundamental constructs for the development of the emergent SSME, ITSM, and Service Oriented Software (SOS) knowledge streams. A diversified literature has provided a richness of findings, but at the same time, the lack of standardized conceptualizations is a source of confusion to IT practitioners and academics. Given this problematic situation, we pose ...

Currently, few projects applying a Model-Driven Engineering (MDE) approach start from high-level requirements models defined exclusively in terms of domain knowledge and business logic. Ontology Engineering (OE) aims to formalize and make explicit the knowledge related to a particular domain. In this vein, this paper presents a modeling approach, formalized in ontological terms, for defining hi...