In assisted reproduction treatments (ART), applying the ICSI method for fertilization of oocytes rather than traditional IVF method, is regarded as controversial two reasons, namely utility and safety. Our study examines an IVF-ICSI Split model couples with unexplained infertility, where male factor meticulously excluded ART conducted by a strict algorithm, commitment to blastocyst culture, alo...

Available for download in Word Document format Summary pFSH therapy for the male suffering from severe OTA or non-obstructive “maturation arrest” azoospermia is beneficial, improving fertilization and implantation rates. It is possible that improved embryo quality, due to improved paternal factor, contributes to these results. Introduction Our group presented recently that pFSH (Metrodin) admin...

background: the latest studies reported that local endometrial injury is a useful method to improve the success of ivf-icsi outcome. objective: to assess whether local endometrial injury occurred by pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent ivf-icsi cycle in patients who had recurrent ivf failure. materials and metho...

Sexed semen (SS) exhibits approximately 80% of the fertilizing ability of conventional semen (CS), and studies have shown that this continues through the 8-cell stage of bovine embryo development. At the time of this study, no information could be found that, when used for IVF and intracytoplasmic sperm injection (ICSI) development, had been carried to the blastocyst stage. In addition, questio...

INTRODUCTION Intracytoplasmatic sperm injection (ICSI) is currently the most frequently used human reproductive technology in Germany. ICSI was introduced as routine, insurance-funded medical care in 2002 by the Federal Joint Committee. A re-evaluation of published literature on malformation rates in children born of ICSI pregnancies within a period of three years formed part of the committee's...

introduction: the aim of this study was to determine the effects of maternal age in fertilization rate of intracytoplasmic sperm injection comparison with ivf. material and methods: in this prospective clinical trial study, 200 couples with male subinfertility that referred to infertility clinic were enrolled. couples were selected on the basis of semen parameters and divided randomly into two ...

BACKGROUND To date the IMSI procedure represents the only real-time and unstained method available to discard spermatozoa with ultrastructural defects. Several studies demonstrated that IMSI provides positive results in couples with severe male factor infertility or repeated ICSI failures. Aim of this pilot study is to evaluate the differences between IMSI and ICSI in terms of IVF outcomes in a...

BACKGROUND GnRH agonist administration in the luteal phase has been suggested to beneficially affect the outcome of intracytoplasmic sperm injection (ICSI) and embryo transfer (ET) cycles. This blind randomized controlled study evaluates the effect of GnRH (Gonadotropine Releasing Hormone) agonist administration on ICSI outcome in GnRH antagonist ovarian stimulation protocol in women with 2 or ...

BACKGROUND In-vitro fertilization (IVF) is the treatment of choice for unresolved infertility. It comprises a number of key steps, each of which has to be negotiated before the next is attempted, but the factors which are associated with failure at each stage have not been reported. METHODS AND FINDINGS We analyzed anonymised national data on women undergoing their first fresh autologous IVF ...

The main perinatal complications of assisted reproduction include congenital malformation, chromosomal aberrations, multiple pregnancy, and prematurity. Earlier studies and in vitro fertilization (IVF) registries showed that there was no increased incidence of congenital malformations in children conceived by IVF/intracytoplasmic sperm injection (ICSI). However, a large Australian study has fou...