Optic nerve hypoplasia with hypopituitarism and intact septum pellucidum is a variant of septo-optic dysplasia or deMorsier's syndrome.' Although neonatal jaundice has been seen with this syndrome, the association with severe prolonged cholestatic jaundice has not been emphasised. We describe three patients who presented with cholestatic jaundice and were found to have optic nerve hypoplasia an...

Background: Neonatal jaundice is clinically presented in 60% of full-term newborns. About 8% of newborns with jaundice have urinary tract infection (UTI) without any other clinical signs in favor of UTI. In present study we evaluated clinical and paraclinical data that help to rapid and early diagnosis of UTI in apparently healthy newborns with jaundice. Methods: From February to August 2006, 5...

INTRODUCTION Jaundice is the yellowish pigmentation of the skin, sclera, and mucous membranes resulting from bilirubin deposition. Children born to mothers with HIV are more likely to be born premature, with low birth weight, and to become septic-all risk factors for neonatal jaundice. Further, there has been a change in the prevention of mother-to-child transmission (PMTCT) of HIV guidelines f...

Cholestatic jaundice and elevated liver enzymes are uncommon, but recognized, manifestations of neonatal thyrotoxicosis. Current guidelines for evaluation of cholestatic jaundice and reviews in Neonatology literature do not discuss hyperthyroidism in the differential diagnosis of cholestatic jaundice. We report two cases of neonatal thyrotoxicosis secondary to neonatal Graves’ disease that pres...

Neonatal jaundice [2] is the yellow discoloration of the skin and eyes due to elevated bilirubin levels in the bloodstream of a newborn. Bilirubin is a byproduct of the breakdown of red blood cells. Jaundiced infants are unable to process bilirubin at a normal rate or they have an abnormally high amount of bilirubin in their bloodstream, resulting in a buildup of the yellow colored bilirubin. T...

Introduction Neonatal cholestasis is defined as prolonged elevation of serum levels of conjugated bilirubin beyond the first 14 days of life. Neonatal hyperbilirubinaemia is usually physiologic, unconjugated, and self-limited. Only 2–15% of neonates remain jaundiced past 2 weeks of life, and just 0.2–0.4% have cholestatic jaundice from either intrahepatic cholestasis or structural abnormalities...

tion in adults is less than 18 mmol/l. Jaundice is best looked for in the sclerae and mucous membrane of the soft palate and is a common sign in almost all liver and biliary tract diseases. There are several important questions of value in determining the diagnosis which the clinician should ask himself/herself: 1 Is the jaundice due to an obstruction of the biliary tree? 2 Is there evidence of...

Intestinal volvulus without malrotation is a rare disease that causes volvulus of the small intestine despite normal intestinal rotation and fixation. We encountered a neonate with this disease who developed early jaundice and was suspected to have a fetal onset. This patient was characterized by early jaundice complicating intestinal volvulus without malrotation and is considered to have exhib...

one old case of jaundice, one case of dysentery, and uix cases of congestive diarrhoea. On 4th April one case of ague was admitted, presenting no peculiarity. On the 6th two cases were admitted, having a distinctly jaundiced appearance ; and from this date to the 25th, 31 cases of ague, with marked hepatic derangement in every instance, and actual jaundice in many ; 4 cases of jaundice without ...