Neurogenesis in the mammalian adult brain is a well established phenomenon (for the recent reviews see Carpentier & Palmer, 2009; Kaneko & Sawamoto, 2009; Rodriguez & Verkhratsky, 2011) that is important in both young and aging brain (Galvan & Jin, 2007; Rao et al., 2006). The subventricular zone, subgranular layer of the dentate gyrus (DG), and cortex are the main sites of adult neurogenesis (...

how to cite this article: mansouri nejad se, yazdan panah mj, tayyebi meibodi n, ashrafzadeh f, akhondian j, beiraghi toosi m, eslamieh h. griscelli syndrome: a case report. iran j child neurol. 2014 autumn;8(4): 72-75. objective griscelli syndrome (gs) is a rare autosomal recessive immune deficiency disorder that presents with pigmentary dilution of the skin and hair, recurrent skin and pulmon...

AMA Wang S, Gao X, Hui H, Li N, Zhou Y, Yin H. Comparison between preoperative hook-wire and liquid material localization for pulmonary nodules: a meta-analysis. Videosurgery Other Miniinvasive Techniques/Wideochirurgia i inne techniki małoinwazyjne. 2023. doi:10.5114/wiitm.2023.130330. APA Wang, S., Gao, X., Hui, H., Li, N., Zhou, Y., & Yin, (2023). https://doi.org/10.5114/wiitm.2023.130330 Ch...

Introduction Methotrexate (MTX) is recommended for children with juvenile idiopathic arthritis (JIA) with persistent oligoarticular course with high disease activity and features of poor prognosis or if they failed intraarticular glucocorticoid steroid injections following the 2011 ACR recommendations for the treatment of JIA. To date efficacy and safety of MTX for this JIA category have not be...

We read with interest the recent publications by Ariyoshi et al. (2011) and Raccor et al. (2011). The role of a number of cytochrome P450 (P450) isozymes in the 4-hydroxylation of cyclophosphamide has been debated for several years. There is evidence that both CYP2B6 and CYP2C19 are important in the biotransformation and activation of this prodrug in vitro (Chang et al., 1993, 1997; Huang et al...

942 INTRODUCTION A central feature of liver function is the ability to metabolize foreign substances and sense pathogens in the circulating blood stream. In order to maintain tissue homeostasis, the liver has the capacity to mount a rapid response to toxin-mediated injury or pathogen infection and regenerate damaged parenchymal tissue. Various cytokines and growth factors and their requisite si...

Regarding our article on the association of androgen deprivation therapy (ADT) with increased Alzheimer’s disease risk, Bowen et al, Froehner and Wirth, Leow et al, and Brady et al highlight a number of significant considerations that will prove important in the design of future studies that investigate the association of ADT and Alzheimer’s disease. We agree with Bowen et al and Leow et al tha...

how to cite this article: inaloo s, haghbin s. multiple sclerosis in children. iran j child neurol. 2013 spring;7(2):1-10.   multiple sclerosis (ms) is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. a total of 4% to 5% of ms population are pediatric. pediatric ms is defined as the appearance of ms before the age of sixteen. about...

Juvenile idiopathic arthritis (JIA) encompasses a range of phenotypes of joint inflammation that begin in childhood. The most distinctive and potentially most severe of these is systemic JIA (sJIA), an intensely inflammatory disease characterized by high spiking fevers and evanescent rashes that sometimes progresses to a devastating chronic polyarthritis. In PNAS, Ombrello et al. establish an u...