AIM To investigate the incidence and risk factors of microscopically positive proximal margins in Chinese patients with adenocarcinoma of the gastroesophageal junction. METHODS The medical records of 483 patients, who underwent surgical treatment with curative intent for adenocarcinoma of the gastroesophageal junction in a single high-volume tertiary medical center, were reviewed. Demographic...

In order to elucidate the role of gap junctions in adrenal cell responses, we measured the effect of inhibiting gap junctions with 18-alpha glycerrhetinic acid (GA; a potent inhibitor of cell-cell communication) and connexin antisense transfection on cell proliferation and adrenocorticotropin (ACTH)-stimulated steroidogenesis. In these experiments we utilized a bovine adrenocortical cell (SBAC)...

BACKGROUND Maple syrup urine disease (MSUD) is an autosomal recessive disorder caused by defective activity of the branched-chain alpha-ketoacid dehydrogenase enzyme complex. Early diagnosis and management of MSUD are imperative for preventing permanent neurological impairments. In the Philippines, a 4.7 kb deletion in the dihydrolipoamide branched-chain transacylase E2 (DBT) gene has been comm...

BACKGROUND AND PURPOSE The aim of this retrospective study was to report the incidence, clinical presentation, and midterm clinical and imaging results of endovascular treatment of 10 aneurysms of the vertebrobasilar junction. MATERIALS AND METHODS Between January 1995 and January 2007, 2112 aneurysms were treated in our institution. Ten aneurysms in 10 patients were located on the vertebroba...

Atrioventricular junction ablation with permanent pacemaker implantation is a highly effective treatment approach in patients with atrial fibrillation and high ventricular rates resistant to other treatment modalities, especially in the elderly or those with severe comorbidities. Compared with pharmacological therapy alone, the so-called "ablate and pace" approach offers the potential for more ...

We present a scattering treatment of transport in S-F-S junctions with a small ferromagnetic metal region inside the junction. The charge carriers are assumed not to thermalize with the fer-romagnet conduction band, and the ferromagnetic and superconductor orders coexist close to the interfaces. This requires a small ferromagnetic region in the junction. Ferromagnetism in the junction provides ...

We discuss the interaction of a tunneling electron with its electromagnetic environment|when the latter either is in equilibrium or includes an applied microwave eld. The environment of an isolated tunnel junction is modeled by a set of harmonic oscillators that are suddenly displaced when an electron tunnels across the junction. We treat these displaced oscillators quantum mechanically, predic...