We describe a high-performance liquid chromatographic procedure for the simultaneous measurement of vitamins K1 and E in human serum. Delipidated human serum (free of vitamins K1 and E) was used to make standard solutions of these vitamins, and cetyl naphthoate and alpha-tocopheryl acetate were the internal standards for vitamin K1 and vitamin E, respectively. A simple, novel separation method ...

The current study investigated the performance of a moving bed biofilm reactor (MBBR), when adding 3D-printed biocarriers fabricated with 13X and bentonite (MBBR 3D), using K1 commercial K1) not at all (control MBBR). For evaluation MBBR efficiency, various physicochemical parameters were measured, while extracted from was evaluated. findings suggest that there is an optimal biodegradation orga...

BACKGROUND Animal studies have shown that vitamin K treatment reduced vascular calcification, but human data are limited. OBJECTIVE We determined the association between vitamin K status and coronary artery calcium (CAC) progression in the Multi-Ethnic Study of Atherosclerosis by using a case-cohort design. DESIGN Serum phylloquinone (vitamin K1) was measured in 296 participants with extrem...

Epidemiological data show that O18:K1 Escherichia coli is a common cause of neonatal bacteremia and meningitis. These bacteria were capable of multiplying in the bloodstream of newborn rats and were resistant to the bactericidal effects of complement in the absence of specific antibodies. The roles played by the O antigen and the K antigen in complement resistance were analyzed by comparing the...

A total of 95 K1 Escherichia coli strains of the O (lipopolysaccharide) serotypes O1, O7, or O18 had been analyzed previously for the ability to cause bacteremia after colonizing the gut of newborn rats. In this study, these strains were tested for their resistance to the bactericidal activity of rat serum. All strains that had caused bacteremia in a high percentage of the inoculated rats were ...

BACKGROUND Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recently been identified as pattern-recognition molecule (PRR) of the lectin complement pathway. CL-K1 is preferentially expressed in the kidneys, but als...

The rate constant for free fatty acid influx (k1) was studied in normal and ischemic myocardium. In 15 normal subjects and 30 patients with coronary artery disease, 201Tl and 15-(p-123I-iodophenyl)-pentadecanoic acid (IPPA) were administered during exercise under fasting conditions and at rest. In 10 patients, the study was repeated after percutaneous transluminal coronary angioplasty; in three...

A binary sequence satisfies a one-dimensional (d; k) run length constraint if every run of zeros has length at least d and at most k. A two-dimensional binary pattern is (d1; k1; d2; k2)-constrained if it satisfies the one-dimensional (d1; k1) run length constraint horizontally and the one-dimensional (d2; k2) run length constraint vertically. For given d1; k1; d2, and k2, the asymmetric two-di...

Grunnet, Morten, Hans-Günther Knaus, Christina Solander, and DanA. Klaerke. Quantification and distribution of Ca21-activated maxi K1 channels in rabbit distal colon. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G22– G30, 1999.—The Ca21-activated maxi K1 channel is an abundant channel type in the distal colon epithelium, but nothing is known regarding the actual number and precise loc...

We recently cloned and characterized the rat kidney-specific organic anion transporter, OAT-K1, which was suggested to mediate renal tubular transport of methotrexate. In this study, we investigated the interactions of nonsteroidal anti-inflammatory drugs (NSAIDs) with OAT-K1 by evaluating the effects of these drugs on renal distribution of methotrexate in vivo, and on methotrexate accumulation...