Alanine-based peptides of defined sequence and length show measurable helix contents, allowing them to be used as a model system both for analyzing the mechanism of helix formation and for investigating the contributions of side-chain interactions to protein stability. Extensive characterization of many peptide sequences with varying amino acid contents indicates that the favorable helicity of ...

I apply the model of semantic universals in terms informativeness/complexity trade-off (Kemp, Xu, and Regier 2018) to Boolean connectives. The explains crosslinguistic absence connective NAND, once theoretical insights from Horn 1972 Katzir Singh 2013 are incorporated. lack NAND follows if languages optimize between (a) simplicity lexicon measured primitive symbols (b) informativeness accurate ...

Martin Erdmann, Dominic Hirschbühl, Christopher Jung, Steffen Kappler, Yves Kemp, Matthias Kirsch, Deborah Miksat, Christian Piasecki, Günter Quast, Klaus Rabbertz, Patrick Schemitz, Alexander Schmidt, Thorsten Walter, Christian Weiser Institut für Experimentelle Kernphysik, Universität Karlsruhe, Wolfgang-Gaede-Str. 1, D-76131 Karlsruhe, Germany contact [email protected] also with CERN, E...

For three decades the biocatalytic version of Kemp elimination 5-nitro-benzisoxazole (1) has served as a forum for testing creation different artificial enzymes, primary aim being to reveal mechanistic intricacies and extend our understanding enzymatic catalysis such. In general, acid/base pertains, but recently novel redox based mechanism was postulated when using P450-BM3 mutants scaffolds. p...

It was in 1987 that McNeal and Bostwick first described intraductal dysplasia during a whole-mount pathologic investigation of 100 prostates without cancer and 100 with cancer that were diagnosed in the pre–prostate-specific antigen era. They found foci of dysplasia in 82% of the prostates harboring cancer compared with 43% in those without cancer. Interestingly, both the grade and volume of dy...

Peter F. Mount, Rebecca E. Hill, Scott A. Fraser, Vicki Levidiotis, Frosa Katsis, Bruce E. Kemp, and David A. Power Austin Research Institute, Department of Nephrology and Department of Medicine, Austin Health, University of Melbourne, Heidelberg, Victoria; St. Vincent’s Institute, Fitzroy, Victoria; and Commonwealth Scientific and Industrial Research Organisation Health Sciences and Nutrition,...

We show that, for sequences of vectors of multiple Wigner integrals with respect to a free Brownian motion, componentwise convergence to semicircular is equivalent to joint convergence. This result extends to the free probability setting some findings by Peccati and Tudor (2005), and represents a multidimensional counterpart of a limit theorem inside the free Wigner chaos established by Kemp, N...