Identical twin sisters with Darier's disease were successfully treated with a combination of oral vitamins A and E after vitamin A alone in a higher dose did not yield a good response. Although synthetic retinoids are currently favoured drugs for disorders of keratinization, the usefulness of the synergistic action of these fat-soluble vitamins is recapitulated and the lack of side -effects whi...

Darier disease (DD) is an autosomal-dominant skin disorder that is characterized by multiple keratotic papules, loss of epithelial adhesion, and abnormal keratinization. We describe an unusual case of late-onset unilateral segmental DD that follows the lines of Blaschko. Our patient did not exhibit other classic findings of DD. Our case and review of the literature suggest that lesions previous...

Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) is a rare disorder of keratinization that clinically resembles comedo nevus but occurs on the palms and soles and is characterized by cornoid lamella in the histopathology. We hereunder report a young male with mildly itchy papules on the lateral surface of the left foot who was diagnosed with PEODDN upon biopsy of the lesion. We brief...

purpose: to report a case of xerophthalmia after bariatric surgery. case report: a 24- year -old man presented to the eye clinic with a 4 -month history of irritable gritty eyes. he complained from night blindness, too. he was being treated for dry eye with artificial tears and ophthalmic ointments during the last month without any significant improvement. his vision was 20/20 unaided in both e...