IMPORTANCE Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral palsy (CP). However, the excess risk for CP among these infants is unknown. OBJECTIVE To quantify the risks for CP and CP consistent with kernicterus that are associated with high TSB levels based on the 2004 American Academy of Pediatrics exchange tra...

hyperbilirubinaemia The study by Keren and colleagues is a retrospective study, using infants in whom preand post-discharge TSB has been carried out, hence causing an inherent bias towards the same group. The data for clinical risk have been collected from documents such as admission, intrapartum, and discharge forms. This retrospective collection can result in missing or ambiguous data, as has...

PURPOSE This study aimed to determine the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among infants with neonatal indirect hyperbilirubinemia (NIH); compare G6PD-deficient and G6PD-normal patients regarding hyperbilirubinemia and need for exchange transfusions (ET); and assess risk factors for ET and kernicterus. METHODS This is a case-control retrospective study. Medica...

This study examined the effect of sensory feedback (e.g., flashing lights and sound) on the imitation performance of children with autism and typical children group-matched for mental age. Participants were administered an immediate object-imitation task with six novel toys constructed for this study: three with a sensory effect that could be activated by imitating the modeled action and three ...

Background: The aim of this study was to perform a systematic review and meta-analysis on available data about glucose-6-phosphate dehydrogenase enzyme deficiency (G6PDD) status in Iranian neonates screened for the disease. Methods: A literature search was conducted in electronic databases of Embase, PubMed, Web of Sciences, Scopus and Google Scholar for articles published from inception to 1 ...

Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal and its progression to kernicterus leading cause death disability among newborns in poorly-resourced countries. OBJECTIVES: To determine the frequency congenital hypothyroidism new born admitted with at tertiary care hospital Peshawar. METHODOLOGY: Settings: removed for blind review Duration: P...

Background: Neonatal seizure is a paroxysmal behavior caused by hyper-synchronous discharge of group neurons. seizures are the most common overt manifestation neurological dysfunction in newborn. The electroencephalography (EEG) an important tool evaluation infant with symptoms referable to central nervous system. It provides excellent and non-invasive method assessing at risk newborns formulat...