the host thyroid. The tumors themselves showed extremely low incorporation, although thyroidectomy of the host significantly increased the incorporation in the tumors. However, results of incorporation experiments do not distinguish the transitional from the autonomous tumors. Tumor growth also caused iodide peroxidase activity in the host thyroid to decline. The enzyme activity in the transiti...

The purpose of this study was to document the accuracy of (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) with sodium iodide detectors in characterizing indeterminate lung nodules or masses and in identifying additional extra-lesional findings. 50 consecutive patients without a confident diagnosis of malignancy on CT underwent (18)FDG PET with and without attenuation cor...

Previous studies have demonstrated that short-term oral iodide administration, in doses ranging from 1500 micrograms to 250 mg/day, has an inhibitory effect on thyroid hormone secretion in normal men. As iodide intake in the USA may be as high as 800 micrograms/d, we investigated the effects of very low dose iodide supplementation on thyroid function. Thirty normal men aged 22-40 years were ran...

Recent studies have highlighted the impact of sea surface iodide concentrations on the deposition of ozone to the sea surface and the sea to air flux of reactive iodine. The use of models to predict this flux demands accurate, spatially distributed sea surface iodide concentrations, but to date, the observational data required to support this is sparse and mostly arises from independent studies...

After the intravenous administration of Il'1labeled L-diiodotyrosine (DIT), an increasing fraction of the labeled iodine of the serum becomes inorganic iodide as the DIT undergoes deiodination. Most of the labeled iodine which appears in the urine is inorganic iodide (1). If one makes an estimate of the renal clearance of inorganic iodide, based on the concentrations of labeled inorganic iodide...

The present work reports an efficient synthesis of fluorinated pyridinium salts-based hydrazones under both conventional and eco-friendly ultrasound procedures. The synthetic approach first involves the preparation of halogenated pyridinium salts through the condensation of isonicotinic acid hydrazide (1) with p-fluorobenzaldehyde (2) followed by the nucleophilic alkylation of the resulting N-(...

introduction: effective debridement of the root canal system with chemical irrigants prior to obturation is the key to long-term success of endodontic therapy. the purpose of this study is to compare the antibacterial activity of 2.5% sodium hypochlorite (naocl) and 2% iodine potassium iodide (iki) solutions as intracanal disinfectant in infected root canals during one-visit endodontic treatmen...

an experiment was conducted to investigate the effect of thyroid gland activity modulation (hyper or hypothyroidism) on energy utilization in broiler chickens. two hundred and forty one-day-old cobb broiler chicks were distributed into three dietary metabolizable energy (me) treatment groups (80 chicks each). the control group (e0) was fed basal diet (3150 kcal/kg diet), the second group (e1) w...

Iodide uptake by the sodium/iodide symporter (NIS) in thyrocytes is essential for thyroid hormone production. Reduced NIS activity has been reported in thyroid diseases, including thyroid cancer and congenital hypothyroidism. The study of iodide uptake in thyrocytes has been limited by the availability of appropriate in vitro models. A new culture technique was recently developed that allows no...