We report a 47-year-old male patient who developed acute kidney injury requiring hemodialysis, associated with massive enlargement of both kidneys. A part from intra-abdominal lymphadenopathy, there was no other organ or lymph node involvement. A kidney biopsy established the diagnosis of non-Hodgkin's lymphoma. The patient received chemotherapy with good response. This case demonstrates that t...

A patient with a known biopsy of polyarteritis nodosa diagnosis presented with cyclic fevers, acute kidney injury, and progression of rash from macular to pustular, worsening despite being on antibiotics, without evidence of infection on multiple cultures. The patient had a pathological diagnosis from a skin biopsy of acute generalized exanthematous pustulosis syndrome, with a total resolution ...

We describe a 61-year-old woman with acute kidney injury, nephrotic range proteinuria and hematuria. Kidney biopsy showed membranous glomerulopathy (MG) with superimposed pauci-immune necrotizing crescentic glomerulonephritis (PNCGN). Coexistent MG and PNCGN is a rare occurrence. The diagnosis of such an exceptionally rare combination relies on the combination of renal biopsy findings and serol...

INTRODUCTION Chronic changes in biopsies from long-term stable kidney allografts have been reported to correlate with graft prognosis. Morphological changes in baseline ('zero-hour') biopsies have been described as well, but their importance for long-term prognosis have been less clear. The aim of the present study was to evaluate biopsy changes from baseline to 1 year after transplantation in ...

This chapter begins with a very brief history of renal pathology, discusses the role of the renal biopsy in the care of patients with kidney disease, and presents basic concepts of pathologic evaluation of kidney diseases. The emphasis in this chapter is on the pathologic evaluation of native kidney lesions in real biopsy specimens, and thus is most relevant to the medical renal diseases covere...

A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal. Kidney and bone marrow biopsy both showed massive infiltration of lymphoblasts of T-cell linage. Renal function normalized rapidly on prednisolone therapy. Kidney involvement in acute lymphob...

BackgroundKidney dysfunction is common after liver transplantation (LT), and often attributed to calcineurin inhibitors (CNIs). Very few studies have looked at histological causes.Material methodsThe study a retrospective analysis of the findings diagnosis in all patients who underwent kidney biopsy LT from 2010-2020. Data are shown as mean ± standard deviation or medians (25-75 interquartile r...

tery stenosis. A kidney biopsy was performed, and considered nondiagnostic, and a new biopsy was performed in 1994. During the following years, renal function gradually deteriorated and she underwent successful deceased donor kidney transplantation in 2007. Patient 2, the daughter of patient 1, was referred to a nephrologist in 1999 at the age of 31. At that stage she had minimal proteinuria (0...

Most patients with SLE develop kidney disease related to this systemic underlying disease process. Lupus nephritis is an important cause of morbidity and even mortality in patients with systemic lupus erythematosus. Lupus nephritis has diverse morphologic manifestations with varying clinical presentations and consequences. The pathogeneses involve immune complexes, which can deposit anywhere in...