The development of dialysis was a dramatic step forward in medicine, allowing people who would soon have died because of lack of kidney function to remain alive for years. We have since found, however, that the "artificial kidney" does not live up fully to its name. Dialysis keeps patients alive but not well. Part of the residual illness that dialysis patients experience is caused by retained w...

The renal mononuclear phagocytic system, conventionally composed of macrophages (Mø) and dendritic cells (DCs), plays a central role in health and disease of the kidney. Overlapping definitions of renal DCs and Mø, stemming from historically separate research tracks and the lack of experimental tools to specifically study the roles of these cells in vivo, have generated confusion and controvers...

To analyze the knowledge and safety of primary health care professionals in management chronic kidney disease its early stages. Integrative literature review carried out four steps. The search took place following databases: MEDLINE via PubMed, Web Science, Scopus BVS. descriptors used were “Primary Health Care” AND “Kidney Diseases” “Health Knowledge, Attitudes, Practice” quality analysis was ...

Kidney diseases are worldwide public health problems affecting millions of people. However, there still limited therapeutic options against kidney diseases. Semaphorin 3A (SEMA3A) is a secreted and membrane-associated protein, which regulates diverse functions, including immune regulation, cell survival, migration angiogenesis, thus involving in the several pathogeneses diseases, eyes neurons, ...

AIM To determine the relationship between chronic kidney disease (CKD) awareness (CKD-A), self-management behaviors (CKD-SMB) knowledge, performance of CKD-SMBs, health literacy (HL) and kidney function. METHODS Participants were eligible patients attending an outpatient nephrology clinic. Participants were administered: Newest Vital Sign to measure HL, CKD self-management knowledge tool (CKD...

Aging kidneys undergo structural and functional changes that decrease autoregulatory capacity and increase susceptibility to acute injury. Acute kidney injury associates with duration and location of hospitalization, mortality risk, progression to chronic kidney disease, and functional status in daily living. Definition and diagnosis of acute kidney injury are based on changes in creatinine, wh...

Several modalities of renal replacement therapy (RRT) are available for the treatment end-stage disease (ESRD). Patients likely to face complex medical decisions regarding type they wish pursue. A prospective, observational, descriptive and cross-sectional survey case series study was carried out in patients with grade 3-5 chronic kidney at General Hospital ‘Dr. Miguel Silva’ without starting t...

The horseshoe kidney is a congenital fusion anomaly where both kidneys are fused at the lower poles. We report a case of horseshoe kidney in a 70 year-old Thai cadaver. This horseshoe kidney was associated with malformations of renal hila, sinuses, calyces and supernumerary arterial supplies from the dorsal part of the kidney. To our knowledge, the arterial supply to the horseshoe kidney from t...