The nuclear-electronic orbital ~NEO! method for the calculation of mixed nuclear-electronic wave functions is presented. Both electronic and nuclear molecular orbitals are expressed as linear combinations of Gaussian basis functions. In the NEO-HF ~Hartree-Fock! method, the energy corresponding to the single-configurational mixed nuclear-electronic wave function is minimized with respect to the...

In psychiatric outpatients, the usefulness of the dimensional NEO-FFI as a screening instrument for personality disorders (PDs) was compared with the categorical screening instrument SAPAS-SR using the SCID-II as the gold standard. Major research questions are: 1) is the NEO-FFI a useful screening instrument for PDs? 2) does the NEO-FFI outperform a categorical screening instrument (SAPAS-SR)? ...

The extent of genetic degeneration of the nec-Y chromosome of Drosophila americana ama'cana has been investigated. Three loci, coding for the enzymes enolase, phosphoglycerate kinase and alcohol dehydrogenase, have been localized to chromosome 4 of D. a. americunu, which forms the neo-Y and neo-X chromosomes. Crosses between D. a. americana, and D. virilis or D. montana showed that the loci cod...

This thesis examines the question: What does a URI mean? Or in other words, what does a URI identify and refer to? This question is of utmost importance for the creation and re-use of URIs on the Semantic Web. An philosophical and historical introduction to the Web explains the primary purpose of the Web as a universal information space for naming and accessing information. A terminology, based...

Platelet activation is a hallmark of severe preeclampsia, and platelet PGH synthase 1-derived (PGHS1-derived) thromboxane A(2) (TxA(2)) has been implicated in its pathogenesis. However, genetic disruption of PGHS1 delays parturition. We created hypomorphic PGHS1 (PGHS1(Neo/Neo)) mice, in which the substantial but tissue-dependent variability in the inhibition of PGHS1-derived eicosanoids achiev...

Purpose: Telecommunications comprises a vital component of information infrastructures and services, with an historically strong public interest dimension. For the best part of 30 years, the telecommunications sector in Europe has been the subject of a radical reorganisation in structural and operational terms along the lines of neo-liberalism. This article analyses the significance of the neo-...