We recently described, in Cannabis sativa, the oldest sex chromosome system documented so far plants (12–28 Myr old). Based on estimated age, we predicted that it should be shared by its sister genus Humulus, which is known also to possess XY chromosomes. Here, used transcriptome sequencing of an F1 family H. lupulus identify and study chromosomes this species using probabilistic method SEX-DET...

The increasing incidence of Multi Drug Resistance Tuberculosis (MDR-TB) and Extensively Drug Resistance TB (XDR-TB) worldwide highlight the urgent need to search for newer anti-tuberculosis compounds. It has been determined that pharmaceutical plant, hops (Humulus lupulus), possesses some antibacterial effect. In this study, the antimycobacterial effect of this plant on rifampin sensitive and r...

This study compares the yields of different extractions methods for a Brazilian variety Humulus lupulus using scCO2, scCO2 + ethanol, ethyl acetate, and compressed propane. Extracts were characterized by total phenolics content (TPC), flavonoid (TFC), antioxidant activity (AA). The extraction from 2.7 to 10.1 wt% when propane at 20 °C 10 MPa acetate 80 25 MPa, respectively. Furthermore, effect ...

Hop stunt viroid (HSVd), a significant pathogen of some hop cultivars, was detected for the first time in hops Australia. Plants were tested graft-transmissible pathogens prior to their use research trials. Upon observing symptoms indicative potential infection, RNA extracted and amplified using reverse transcription polymerase chain reaction (RT-PCR); HSVd identity confirmed by sequencing.

An isotope dilution method using [1-(13)C]sodium (Na) acetate was conducted to determine the effect of feeding hop (Humulus lupulus L.) residues on plasma acetate metabolism in six adult crossbred sheep. The sheep were fed 63 g/kg BW(0.75)/d of either mixed hay (MH-diet) of orchardgrass (Dactylis glomerata L.) and reed canarygrass (Phalaris arundinacea L.) at a 60:40 ratio or MH-diet and hop-re...

Humulus lupulus L. (hops) is a popular botanical dietary supplement used by women as a sleep aid and for postmenopausal symptom relief. In addition to its efficacy for menopausal symptoms, hops can also modulate the chemical estrogen carcinogenesis pathway and potentially protect women from breast cancer. In the present study, an enriched hop extract and the key bioactive compounds [6-prenylnar...

The polyphenol-enriched fraction of an ethanolic hops extract (Humulus lupulus) was separated to provide four acylphloroglucinol-glucopyranosides (1-4). 1-(2-Methylpropanoyl)phloroglucinol-glucopyranoside 1 has been isolated from hops before, whereas 1-(2-methylbutyryl)phloroglucinol-glucopyranoside 2, known as multifidol glucoside, and 1-(3-methylbutyryl)phloroglucinol-glucopyranoside 3 were f...

The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth in the presence of 5 mg/L of xanthohumol than cultures with only H2O2. Likewise, DNA damage assessed by the comet assay was significantly lowe...