نتایج جستجو برای: lactam antibiotics among gram
تعداد نتایج: 1278677 فیلتر نتایج به سال:
Rothia sp. are Gram-positive bacteria in the class of Actinobacteria that part physiological oral flora. In rare cases, aeria and dentocariosa can cause infective endocarditis (IE). The biofilm potential is unknown. Specimen from two cases were obtained during cardiac surgery. One patients suffered mitral valve IE aeria. other case, a prosthetic pulmonary was caused by dentocariosa. Fluorescenc...
Several new beta-lactam antimicrobial agents have been introduced in the last few years. In this investigation, the in vitro activities of several recently introduced cephalosporins (cefoperazone, cefotaxime, ceftazidime, and ceftizoxime), moxalactam, and N-formimidoyl thienamycin were compared with those of cefoxitin, clindamycin, and metronidazole against 203 strains of anaerobic bacteria. At...
Fifty-four milk samples from commercial sources that tested positive for beta-lactam antibiotics were analyzed by a multiresidue liquid chromatographic (LC) procedure based on LC fractionation. Penicillin G and cephapirin were the beta-lactam antibiotics found most frequently. Some samples did not contain detectable beta-lactam antibiotics. In a few, the presence of a beta-lactam antibiotic was...
BACKGROUND Community-acquired pneumonia (CAP) 2007 guidelines from the Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) recommend a respiratory fluoroquinolone or beta-lactam plus macrolide as first-line antibiotics for adults hospitalized with CAP. Few studies have assessed guideline-concordant antibiotic use for patients hospitalized with CAP after the 2007 IDSA/A...
Introduction & Objective: One of the mechanisms of antibiotic resistance in gram negative bac-teria, particularly Klebsiella pneumonia strains, is the production of Extended-Spectrum β lactamase enzymes (ESBLs). Encoding genes of ESBLs are usually located on the plasmid and they are able to transfer to other gram-negative bacteria. Thus, due to the importance of resistance pattern recogniti...
β-lactam antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a β-lactam nucleus in its molecular structure. Till now β-lactams like penicillins, cephalosporins, monobactams, and carbapenems have been developed. Resistance to various β-lactam antibiotics among target pathogens were started with its first use.The most widespread and important cause is th...
Beta-lactamase acquisition is the most prevalent basis for Gram-negative bacteria resistance to the beta-lactam antibiotics. The mechanism used by the most common class A Gram-negative beta-lactamases is serine acylation followed by hydrolytic deacylation, destroying the beta-lactam. The ab initio quantum mechanical/molecular mechanical (QM/MM) calculations, augmented by extensive molecular dyn...
The widespread emergence of methicillin-resistant Staphylococcus aureus (MRSA) has dramatically eroded the efficacy of current β-lactam antibiotics and created an urgent need for new treatment options. We report an S. aureus phenotypic screening strategy involving chemical suppression of the growth inhibitory consequences of depleting late-stage wall teichoic acid biosynthesis. This enabled us ...
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