ESBL (extended-spectrum-β-lactamase)-positive Enterobacteriaceae, which colonized European soldiers in tropical Western African Mali, were subjected to a molecular assessment of their resistance determinants. By doing so, a better insight into the locally endemic pattern of ESBL-associated β-lactamase genes was aspired. From a previous study on diarrhea in European soldiers on deployment in tro...

Therapeutic options for infections caused by gram-negative organisms expressing plasmid-mediated AmpC beta-lactamases are limited because these organisms are usually resistant to all the beta-lactam antibiotics, except for cefepime, cefpirome, and the carbapenems. These organisms are a major concern in nosocomial infections and should therefore be monitored in surveillance studies. Six families...

Metallo-β-lactamase-producing Pseudomonas aeruginosa (MPPA) is an important nosocomial pathogen that shows resistance to all β-lactam antibiotics except monobactams. There are various types of metallo-β-lactamases (MBLs) in carbapenem-resistant P. aeruginosa including Imipenemase (IMP), Verona integron-encoded metallo-β-lactamase (VIM), Sao Paulo metallo-β-lactamase (SPM), Germany imipenemase (...

Abstract. Al-Hadeithi ZSM, Jasim SA, Salahdin OD. 2022. Relation between resistance of Klebsiella pneumoniae to certain antibiotics and ESBL/PBP genes. Biodiversitas 23: 3902-3906. One the most effective on microbes or in treating infections caused by these resistant microbes, as it belongs beta-lactam group such cephalosporin carbapenems, which are considered among important that have wide act...

Background and objectives: Metallobeta-lactamase production is one of the most important mechanisms of antibiotic resistance. The aim of the present study was to evaluate the antibacterial activity of Stachys lavandulifolia and Quercus brantii on the IMP-type metallo-beta-lactamase-producing Pseudomonas aeruginosa. Methods: This study...

Background: Plasmid mediated quinolone resistance (PMQR) has been shown to play an important role in resistance not only to quinolones, but also β-lactams and aminoglycosides. In fact, qnr genes are frequently carried along with β-lactamase determinants on the same plasmids. We studied the prevalence of qnrA, qnrB, qnrS and aac(6’)-Ib-cr genes among quinolone and cephalosporin resistant clinica...

Objectives: Organisms harboring multiple plasmid mediated β-lactamases are major concerns in nosocomial infections. Among these plasmid mediated β-lactamases, ACT (EBC family) is a clinically important enzyme capable of hydrolyzing broad spectrum cephalosporins. Therefore, the present study was undertaken to determine the prevalence of ACT determinant along with other co-existing β-lactamase ge...

Antibiotic resistance genes (ARGs) pose a widespread concern for human health and wastewater treatment plants (WWTPs) are considered to be major source of ARG transmission. In this paper, the potential hosts genetic characteristics ARGs in influent, activated sludge effluent WWTPs Xinjiang were studied by metagenomics. Bacitracin gene (bacA), beta-lactamase (class A beta-lactamase), multidrug (...

conclusions the high prevalence of oxa β-lactamase and high genetic diversity of p. aeruginosa indicated that the resistance of p. aeruginosa might be expanding in our studied hospitals. background pseudomonas aeruginosa is main bacterial pathogen accountable for nosocomial infections. furthermore, it could potentially become resistant to β-lactams, aminoglycosides and fluoroquinolones antibiot...