This statistical primer presents the landmark analysis method, exploring its appropriate use and interpretation while recognizing its limitations. This observational method is used for comparing time-to-event outcome between groups determined during study follow-up. The goal of the landmark method is to estimate in an unbiased way the time-to-event probabilities in each group conditional on the...

This paper proposes a novel method for image registration of lung CT scans. Our approach consists of a procedure for automatically establishing landmark correspondences in lung CT scan pairs and an elaborate variational image registration scheme. The landmark information is incorporated into the registration scheme as pre-registration using the landmark-based Thin-Plate-Spline (TPS) method. The...

This paper introduces methods for automatic annotation of landmark photographs via learning textual tags and visual features of landmarks from landmark photographs that are appropriately location-tagged from social media. By analyzing spatial distributions of text tags from Flickr’s geotagged photos, we identify thousands of tags that likely refer to landmarks. Further verification by utilizing...

This paper presents a novel landmark-based shape deformation method. This method effectively solves two problems inherent in landmark-based shape deformation: (a) identification of landmark points from a given input image, and (b) regularized deformation of the shape of an object defined in a template. The second problem is solved using a new constrained support vector machine (SVM) regression ...

One important problem in the human brain mapping research is to locate the important anatomical features. Anatomical features on the cortical surface are usually represented by landmark curves, called sulci/gyri curves. These landmark curves are important information for neuroscientists to study brain disease and to match different cortical surfaces. Manual labelling of these landmark curves is...

We investigated the echolocating bat's use of an acoustic landmark for orientation in a complex environment with no visual information. Three bats of the species Eptesicus fuscus were trained to fly through a hole in a mist net to receive a food reward on the other side. In all experiments, the vocal behavior of the bats was recorded simultaneously using a high-speed video recording system, all...

Successful wayfinding requires accurate encoding of two types of information: landmarks and the spatial relations between them (e.g. landmark X is left/north of Y). Although both types of information are crucial to wayfinding, behavioral and neurological evidence suggest that they have different substrates. In this paper, we consider the nature of the difference by examining comprehension times...