OBJECTIVES To determine the incidence of Helicobacter pylori (HP) stool antigen (HPSA) in patients with laryngopharyngeal reflux disease (LPRD), and to make a comparison of 2 treatment regimens that have been used based on the presence or absence of HPSA positivity in patients with LPRD. DESIGN Randomized controlled study. SETTING Suez Canal University Hospital, Ismalia, Egypt. PATIENTS A...

OBJECTIVES Laryngopharyngeal reflux (LPR) may be a contributing factor in chronic hoarseness. The association of LPR with functional dysphonia (FD), the most common voice clinic diagnosis, is unknown. We attempted to determine whether patients with FD have a higher rate of laryngeal exposure to acidic stomach contents than do healthy volunteers. METHODS We recruited through the voice clinic 2...

s of all retrieved studies. The full text of the selected studies were then analyzed to ensure that the following inclusion criteria were met: prospective study design, a patient population with a diagnosis of LPR, treatment arm including a prokinetic agent with or without the concomitant use of an antacid therapy (e.g., PPI or H2 antagonist), presence of a comparison arm, and treatment outcome...

Introduction Laryngopharyngeal reflux (LPR) is a highly prevalent disease and commonly encountered in the otolaryngologist's office. Objective To review the literature on the diagnosis and treatment of LPR. Data Synthesis LPR is associated with symptoms of laryngeal irritation such as throat clearing, coughing, and hoarseness. The main diagnostic methods currently used are laryngoscopy and pH m...

There is a lack of consistent guidelines and consensus for the diagnosis of laryngopharyngeal reflux (LPR). A therapeutic trial with a proton pump inhibitor (PPI) has been suggested to identify patients with LPR. This review focuses on the current difficulties in diagnosing the disease and examines the evidence for the effectiveness of PPI therapy in suspected reflux-related laryngeal symptoms....

IMPORTANCE This study shows factors affecting lingual tonsil hypertrophy (LTH) in sleep-disordered breathing. OBJECTIVE To identify the factors associated with LTH in adults with sleep-disordered breathing. DESIGN Retrospective analysis. SETTING Academic tertiary referral center. PARTICIPANTS Ninety-seven adult patients with obstructive sleep apnea, who visited the Department of Otorhin...

About 40% of the population will experience chronic cough at some point during their lives and it tends to be more common in women (Thorax 58:901-7, 2003). Post-nasal drip (or upper airway cough syndrome), gastro-esophageal reflux disease and asthma are considered the most common causes. Yet only a small percentage of patients with these common conditions experience chronic cough. Also there is...

Gastroesophageal reflux disease (GERD) is one of the most common reasons for referral to a physician. reflux-associated extraesophageal symptoms occur in every third patient with GERD. Diagnostic difficulties and prescription effective treatment rapid resolve GERD are still important issues when managing these patients. This paper summarizes data on prevalence pattern symptoms, as well efficacy...