Pseudomonas aeruginosa is the predominant microorganism in chronic lung infection of cystic fibrosis patients. The chronic lung infection is preceded by intermittent colonization. When the chronic infection becomes established, it is well accepted that the isolated strains differ phenotypically from the intermittent strains. Dominating changes are the switch to mucoidity (alginate overproductio...

Development of β-lactam resistance, production of alginate and modulation of virulence factor expression that alters host immune responses are the hallmarks of chronic Pseudomonas aeruginosa infection in cystic fibrosis patients. In this study, we propose that a co-regulatory network exists between these mechanisms. We compared the promoter activities of ampR, algT/U, lasR, lasI, rhlR, rhlI and...

Abstract Funding Acknowledgements Type of funding sources: None. Background Left atrial reverse remodeling has been defined relying on changes in left volume following specific procedures. Little is known about functional assessment the atrium by strain and emptying fraction (LAEF) edge-to-edge mitral repair. Purpose The aim this study to assess function speckle tracking echocardiography LAEF, ...

The Journal of Clinical Investigation | November 2003 | Volume 112 | Number 10 Quorum sensing in Pseudomonas aeruginosa Pseudomonas aeruginosa is a Gram-negative organism that is commonly found in soil and water. Although P. aeruginosa can survive under multiple harsh conditions, it is an opportunistic pathogen and is only able to infect hosts with defective immune system function, such as that...

Abstract Background 4-Dimensional Automated Left Atrial Quantification (4D Auto LAQ) is a technique that uses 3D volume data to determine LA strain. Mitral Valve MVQ) evaluates anatomical and functional mitral valve parameters. Our study evaluated patients with dilated cardiomyopathy tried find correlation between strain apparatus geometry. Methods We enrolled 61 25 healthy volunteers. The eval...

B Full model 4 B.1 Derivation from chemical reactions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 B.2 Non-dimensionalisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 B.3 Empirical alteration of the ”Hill coefficient” . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 B.4 Inducible expression of LuxR/LasR . . . . . . . ....

We report a chemical solution based method using nanoporous track-etched polymer templates for producing long and oriented LaSr-2 × 4 manganese oxide molecular sieve nanowires. Scanning transmission electron microscopy and electron energy loss spectroscopy analyses show that the nanowires are ferromagnetic at room temperature, single crystalline, epitaxially grown and self-aligned.

± Current Address: Department of Microbiology, University of Washington School of 21 Medicine, 1959 NE Pacific St., Room K-360, Seattle, WA 98195-7242. 22 23 ね Current address: Department of Molecular, Cellular and Developmental Biology, 24 219 Prospect St., Yale University, New Haven, CT 06471 25 26 * Corresponding author. Mailing address: Department of Molecular, Cellular and 27 Developmental...

Pseudomonas aeruginosa is a well-known pathogenic bacterium that forms biofilms and produces virulence factors via quorum sensing (QS). Interfering with normal QS interactions between signal molecules and their cognate receptors is a developing strategy for attenuating its virulence. Here we tested the hypothesis that 6-gingerol, a pungent oil of fresh ginger, reduces biofilm formation and viru...