background: the final objective of root canal therapy is to create a hermetic seal along the length of the root canal system. for this purpose, many methods and materials have been introduced. the purpose of this study was to compare the apical microleakage in a new obturation technique (true-tug-back) with two other obturation techniques (lateral condensation and chloroform dip technique). met...

PURPOSE To study the differences in disease caused by two wild-type strains of Candida albicans in a model of contact lens-facilitated keratitis in rabbits. METHODS Two strains, SC5314 and VE175, were examined. Standardized inocula were placed on the debrided corneal surface of one eye in Dutch belted rabbits and covered with a contact lens. A temporary tarsorrhaphy was opened after 24 hours ...

Precise coordination of progenitor cell proliferation and differentiation is essential for proper organ morphogenesis and function during mammalian development. The mitogen-activated protein kinase kinase kinase 1 (MAP3K1) has a well-established role in anterior eyelid development, as Map3k1-knockout mice have defective embryonic eyelid closure and an `eye-open at birth' (EOB) phenotype. Here, ...

The corneal epithelium consists of stratified epithelial cells, sparsely interspersed with dendritic cells (DCs) and a dense layer of sensory axons. We sought to assess the structural and functional correlation of DCs and sensory nerves. Two morphologically different DCs, dendriform and round-shaped, were detected in the corneal epithelium. The dendriform DCs were located at the sub-basal space...

Introduction: This study aims to report a rare case of a respiratory epithelial adenomatoid hamartoma (REAH) of the lateral nasal wall that had initially presented as a fungating mass, similar to that of a sinonasal malignancy, and its complete removal from the lateral nasal wall.   Case Report: We report the case of a 58-year-old woman who presented to us with a chief complaint of recurrent ri...

congenitally missing of maxillary lateral incisors is one of the most common patterns of hypodontia. this paper presents a nine year old boy with congenital missing of lateral incisors. familial history showed that, his mother, aunts, uncle and grandmother have also congenital absence of lateral incisors.

the developmental abnormality of tooth resulting from the infolding of enamel/dentin into the root is called dens invaginatus. management of such cases is usually challenging due to the morphological complexity of root canal system. this report presents a rare treatment protocol of a clinical case of oehler’s type iii dens invaginatus combined with an endodontic lesion in a vital maxillary late...

objectives: patients suffering from mild to moderate knee osteoarthritis may be treated with unloader knee orthoses or laterally wedged insoles. the aim of this study was to identify and compare the effects of two orthoses in these patients. methods: 56 patients with medial compartment knee oa were evaluated when wearing an unloader knee orthosis and insoles with a 6° lateral wedge which were r...