Among divalent cations, the ionophore monensin shows high activity and selectivity for the transport of lead ions (Pb2+) across phospholipid membranes. When coadministered to rats that were receiving meso-dimercaptosuccinate for treatment of Pb intoxication, monensin significantly increased the amount of Pb removed from femur, brain, and heart. It showed a tendency to increase Pb removal from l...

the electrochemical behaviour of lead electrode in hydrochloride solution containing variousoxo-anions at different concentrations was studied by using of cyclic voltammetry (cv) method.results obtained show that the addition of these inorganic compounds decreases the anodic andcathodic currents peaks according to the following order: h2po4- > hpo42-> so42-. it’s revealedalso that the cathodic ...

as axon guidance cues. Both plexin B1 and plexin B2 are expressed during mouse kidney development. Inbred plexin B2 knockout (PB2 KO) mice die prenatally with defects in olfactory bulb development, neuronal proliferation and neural tube closure (exencephaly). We report here that these PB2 KO mice have defects also in kidney morphogenesis. In PB2 / embryos the kidneys are smaller and the number ...

Lead, a toxic heavy metal, is considered one of the most serious pollutants in water environment, posing grave threat to human health and global ecosystem. In this work, simple, fast sensitive sensor strategy for detecting trace lead ions (Pb2+) was proposed. The disposable electrochemical fabricated with screen-printed carbon electrode (SPCE), working modified single step situ polymerized phyt...

BACKGROUND Abdominal colic, constipation and delay in gastric emptying are symptoms of lead poisoning, but there is scant information about the effect of lead on gastric motility. In the present study, we investigated the effect of lead acetate on gastric motility in rats. METHODS Animals were divided into nine groups (n=8); four groups were exposed to lead acetate solution (1%) for 1, 2, 3, ...

BACKGROUND The usage of polynuclear metal clusters as secondary building units (SBU's) in designing of metal organic frameworks (MOF's) is a field of current interest. These metal clusters have attracted a great deal of attention not only due to their interesting structural topologies but also due to promising physical and chemical properties. In this regard various d,f block (transition and la...

The influenza virus polymerase complex, consisting of the PA, PB1, and PB2 subunits, is required for the transcription and replication of the influenza A viral genome. Previous studies have shown that PB1 serves as a core subunit to incorporate PA and PB2 into the polymerase complex by directly interacting with PA and PB2. Despite numerous attempts, largely involving biochemical approaches, a s...

This study mainly centered on the preconcentration and flame atomic absorption spectrometric determination of lead ions by cloud point extraction (CPE) procedure. Complexation Pb2+ vitamin B6 prior to its was achieved in method. The solution pH, surfactant concentrations, interfering ions, incubation temperature sample volume were optimized. limit quantication (LOQ) detection (LOD) values metho...

sub chronic exposure to lead in rats slows gastric emptying, but little is known about the effects of lead on gastric secretion. this study was designed to investigate the effects of lead on gastric acid secretion and its possible mechanisms in rats. lead acetate was dissolved in drinking water in a concentration of 1%. sodium acetate-containing water with a molar concentration similar to lead ...

Research on compact, flexible optical sensors for water quality monitoring, specifically targeting heavy metal ion has become extremely important due to the increasing number of pollution incidents seen worldwide where such metals are involved. Optical fiber-based provide an excellent basis creating new sensing solutions across a wide area, including energy, healthcare, structural defense and i...