Background. Myocardial stretch and increased ventricular filling can lead to increased rates of myocardial protein synthesis. In animal studies, left ventricular mass increases after pericardiectomy, suggesting relief of a biologically meaningful restraining role and a resultant stimulus for growth. The present study was designed to test the hypothesis that combined thoracotomy and pericardioto...

BACKGROUND Myocardial stretch and increased ventricular filling can lead to increased rates of myocardial protein synthesis. In animal studies, left ventricular mass increases after pericardiectomy, suggesting relief of a biologically meaningful restraining role and a resultant stimulus for growth. The present study was designed to test the hypothesis that combined thoracotomy and pericardiotom...

Progressive left ventricular hypertrophy is the hallmark of cardiac manifestations in patients with Fabry disease. Cardiovascular magnetic resonance with tissue tagging allows detailed assessment of the cardiac motion pattern. The aim was to test the hypothesis that not only Fabry patients with severe left ventricular hypertrophy exhibit changes in myocardial motion, but also Fabry patients wit...

Abbreviations: BSA – basic surface area, H-LVH – hypertension with left ventricular hypertrophy, H­NLVH – hypertension with­ out left ventricular hypertrophy, IVST – interventricular septum thickness in diastole, LEPR – leptin receptor, LVDd – left ven­ tricular end­diastolic diameter, LVH – left ventricular hypertro­ phy, LVM – left ventricular mass, LVMI – left ventricular mass index, PVST – ...